Cefteram pivoxil

Cefteram pivoxil Basic information
Product Name:Cefteram pivoxil
Synonyms:2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetylamino]-3-(5-methyl-2H-tetrazol-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;CEFTERAM;Cefteram pivoxil;(+)-(6R,7R)-7-[(Z)-2-(2-Amincr4-thiazolyl)-2-(methoxyimino)acetami-do]-3-[(5-methyl-2H-tetrazol-2-y1)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Ceftetrame;Ro-19-5247;T-2525;Tomimn
CAS:82547-58-8
MF:C16H17N9O5S2
MW:479.49
EINECS:
Product Categories:Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:82547-58-8.mol
Cefteram pivoxil Structure
Cefteram pivoxil Chemical Properties
Melting point >175°C (dec.)
density 1.95±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
pka2.62±0.50(Predicted)
form Solid
color White to Pale Yellow
InChIKeyXSPUSVIQHBDITA-RKYNPMAHSA-N
SMILESN12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(CN1N=NC(C)=N1)=C2C(O)=O
CAS DataBase Reference82547-58-8(CAS DataBase Reference)
Safety Information
MSDS Information
Cefteram pivoxil Usage And Synthesis
DescriptionCefteram pivoxil is an orally-active cephalosponn antibiotic with a broad spectrum of activity. It is reportedly effective against Cirrobacrer, indole-positive Proreus and Enrerobacrer species resistant to cefaclor, cephalexin and amoxicillin. Cefteram pivoxil is indicated primarily for urinary tract infections.
Chemical PropertiesPale Yellow Solid
OriginatorToyama (Japan)
UsesOrally active cephalosporin antibiotic, antibacterial.
DefinitionChEBI: Cefteram is a cephalosporin compound having (5-methyl-2H-tetrazol-2-yl)methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups; a third-generation cephalosporin antibiotic.
Brand nameTomiron
Antimicrobial activityA semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefteram pivoxil. Activity is similar to that of cefixime, but with slightly better activity against staphylococci and some Gram-negative rods.
Available in Japan.
Cefteram pivoxil Preparation Products And Raw materials
Raw materialsTrifluoroacetic acid-->Sulfolane-->7-Aminocephalosporanic acid-->Tetrazole-->TRIMETHYLSILANE
Preparation ProductsCefteram pivoxil
Cefetamet hydrochloride 4'-Methoxyacetophenone Ceftizoxime 4-Methoxybenzylchloride Anisole 2-(2-AMINO-THIAZOL-4-YL)-ACETAMIDE Cefteram pivoxil (Trifluoromethoxy)benzene Cefteram pivoxil Methyl 3-oxovalerate p-Anisic acid p-Anisidine 4-Thiazoleacetamide Cefditoren pivoxil p-Anisaldehyde Methyl isobutyrylacetate Methyl benzoylformate 3-Methoxybenzaldehyde

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.