Fluticasone

Fluticasone Basic information
Product Name:Fluticasone
Synonyms:(6s,9s,10s,11s,13s,14s,16r,17r)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;FLUTICASONE;FluticasonePropionate98.5%;Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6.alpha.,11.beta.,16.alpha.,17.alpha.)-;6α,9-Difluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester;6α,9-Difluoro-16α-methyl-11β-hydroxy-17-hydroxy-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester;Fluticasone Dipropionate;Androsta-1,4-diene-17- Carbothioic acid, 6,9-difluoro- 11,17-dihydroxy-16-Methyl-3- oxo-, S-(fluoroMethyl) ester, (6α,11β,16α,17α)-
CAS:90566-53-3
MF:C22H27F3O4S
MW:444.51
EINECS:
Product Categories:API
Mol File:90566-53-3.mol
Fluticasone Structure
Fluticasone Chemical Properties
Melting point 237-239 °C
Boiling point 553.2±50.0 °C(Predicted)
density 1.37±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Acetonitrile (Slightly), Chloroform (Slightly)
pka11.66±0.70(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic, Unstable in Solution
CAS DataBase Reference90566-53-3(CAS DataBase Reference)
Safety Information
Hazardous Substances Data90566-53-3(Hazardous Substances Data)
MSDS Information
Fluticasone Usage And Synthesis
Usestherapeutic for asthma and allergic rhinitis Flonase
UsesFluticasone is an inhaled corticosteroid used in the treatment of respiratory diseases.
DefinitionChEBI: A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis.
Brand nameCutivate (Altana); Flonase (GlaxoSmithKline); Flovent (GlaxoSmithKline).
Fluticasone Preparation Products And Raw materials
(r)-budesonide FLUTICASONE PROPIONATE INTERMEDIATE 17-Carboxylic Acid Compound (Fluticasone Stage-1) Fluticasone-d3 17-Carboxylic Acid Fluticasone propionate-d5 Fluticasone Propionate - C25H31F3O5S,fluticasone17-propionat FLUTICASONE IMPURITY D Fluticasone 17b-Carboxylic Acid,Fluticasone 17-Carboxylic Acid Fluticasone-d3 17b-Carboxylic Acid FLUTICASONE PROPIONATE RESOLUTION MIXTURE (25 MG) FLUTICASONE FUROATE Fluticasone 17-Thiopropionate Compound {Fluticasone Stage-Ill) Fluticasone related compound A 1,4-DIENE-17.BETA.-CARBOTHIOIC ACID-17-PROPIONATE (FOR FLUTICASONE PROPIONATE) FLUTICASONE-D3 PROPIONATE FLUTICASONE S-METHYL IMPURITY FLUTICASONE PROPIONATE, 17-BETA CARBOXYLIC ACID

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