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| | Intermediate of Rolapitant Basic information |
| Product Name: | Intermediate of Rolapitant | | Synonyms: | Intermediate of Rolapitant;(2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate;3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)-;3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID | | CAS: | 205654-80-4 | | MF: | C23H19NO4 | | MW: | 373.4 | | EINECS: | | | Product Categories: | | | Mol File: | 205654-80-4.mol |  |
| | Intermediate of Rolapitant Chemical Properties |
| Boiling point | 591.6±50.0 °C(Predicted) | | density | 1.270±0.06 g/cm3(Predicted) | | pka | -3.96±0.60(Predicted) |
| | Intermediate of Rolapitant Usage And Synthesis |
| Uses | (2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting. |
| | Intermediate of Rolapitant Preparation Products And Raw materials |
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