2-Methyl-1,3-cyclopentanedione

2-Methyl-1,3-cyclopentanedione Basic information

Product Name:	2-Methyl-1,3-cyclopentanedione
Synonyms:	2-METHYLCYCLOPENTAN-1,3-DIONE;2-METHYL-1,3-CYCLOPENTANEDIONE;METHYLCYCLE-D;2-Methylcyclopentane-1,3-dione,98%;2-METHYL-1,3-CYCLOPENTANEDIONE(METHYLCYCLO-D);2-Methyl-1,3-cyclopentanediolne;2-Methyl-1;2-Methyl-1,3-dioxocyclopentane
CAS:	765-69-5
MF:	C6H8O2
MW:	112.13
EINECS:	212-153-2
Product Categories:	Miscellaneous;ketone;C3 to C6;Carbonyl Compounds;Ketones
Mol File:	765-69-5.mol

2-Methyl-1,3-cyclopentanedione Chemical Properties

Melting point	212-215 °C (lit.)
Boiling point	213°C (estimate)
density	1.0795 (rough estimate)
refractive index	1.4550 (estimate)
storage temp.	Store below +30°C.
solubility	Solubility in hot Methanol (almost transparency).
form	Crystalline Powder
pka	10.83±0.20(Predicted)
color	Light beige to tan
PH	2.95 at 24.7℃ and 10g/L
BRN	1237255
InChIKey	HXZILEQYFQYQCE-UHFFFAOYSA-N
LogP	-0.8 at 30℃ and pH7.66
CAS DataBase Reference	765-69-5(CAS DataBase Reference)
NIST Chemistry Reference	1,3-Cyclopentanedione, 2-methyl-(765-69-5)

Safety Information

MSDS Information

2-Methyl-1,3-cyclopentanedione Usage And Synthesis

Chemical Properties	LIGHT BEIGE TO TAN CRYSTALLINE POWDER
Uses	2-Methyl-1,3-cyclopentanedione hs been used to explore deoxycholic acid (DCA) induced changes in cell signaling. DCA is a secondary bile acid implicated in numerous pathological conditions. It has also been used in the synthesis of (-)-curcumanolide A and (-)-curcumalactone by aldol-lactonization.
Uses	2-Methyl-1,3-cyclopentanedione was used as a reactant in the identification and characterization of benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.
Synthesis Reference(s)	Synthetic Communications, 19, p. 373, 1989 DOI: 10.1080/00397918908050676

2-Methyl-1,3-cyclopentanedione Preparation Products And Raw materials

Raw materials	4-Hydroxy-2-methyl-1,3-cyclopentanedione-->5-Methylcyclopentane-1,2,4-trione-->ethyl 2-(3-methyl-2,4,5-trioxocyclopentyl)-2-oxoacetate-->1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE-->1,3-Cyclopentanedione-->Diphenylmethane-->Fluorene-->Succinic acid-->Acetaldehyde-->Propionyl chloride-->tert-Butyl peroxybenzoate-->Succinic anhydride-->1,1-Dimethoxyethane-->1,4-Cyclohexanedione
Preparation Products	2-[2-(6-methoxytetralin-1-ylidene)-ethyl]-2-methylcyclopentane-1,3-dione

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