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| | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Basic information |
| Product Name: | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine | | Synonyms: | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine;(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;3-(4-Phenoxy-phenyl)-1-(R)-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine;Btk inhibitor 1 (R enantioMer);ibrutinib N-1;Ibrutinib intermeidate N-1;3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyriMidin-4-aMine;3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | | CAS: | 1022150-12-4 | | MF: | C22H22N6O | | MW: | 386.45 | | EINECS: | 200-001-8 | | Product Categories: | Ibrutinib;Intermediates | | Mol File: | 1022150-12-4.mol | ![3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Structure](CAS/GIF/1022150-12-4.gif) |
| | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Chemical Properties |
| Melting point | 133-136oC | | Boiling point | 626.3±55.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 9.00±0.10(Predicted) | | form | Solid | | color | White to Pale Yellow |
| | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Usage And Synthesis |
| Description | IBT6A is a Btk kinase inhibitor. This compound is a precurser for the manufacture of ibrutinib. | | Uses | (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton''s tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives. |
| | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Preparation Products And Raw materials |
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