2,4,6-Triisopropylbenzenesulfonyl chloride

2,4,6-Triisopropylbenzenesulfonyl chloride Basic information
Product Name:2,4,6-Triisopropylbenzenesulfonyl chloride
Synonyms:TPSCL 2,4,6-TRIISOPROPYLBENZENESULFONYL HYDRAZIDE;2,4,6-TRIISOPROPYLBENZENESULFONYL CHLORI;2,4,6-Tris(isopropyl)benzenesulphonyl chloride 98+%;2,4,6-Tris(prop-2-yl)benzenesulphonyl chloride;2,4,6-tris(propan-2-yl)benzene-1-sulfonyl chloride;2,4,6-three isopropylbenzene sulfonyl chloride;2,4,6-TRIISOPROPYLBENZENESULFONYL CHLORIDE97%;2,4,6-Triisopropylbenzenesulfonic acid chloride
CAS:6553-96-4
MF:C15H23ClO2S
MW:302.86
EINECS:229-479-6
Product Categories:API intermediates;Biochemistry;Condensation & Active Esterification;Condensing Agents (DNA / RNA Synthesis);Nucleosides, Nucleotides & Related Reagents;Protecting Agents, Phosphorylating Agents & Condensing Agents;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Sulfonyl Halides;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfur Compounds
Mol File:6553-96-4.mol
2,4,6-Triisopropylbenzenesulfonyl chloride Structure
2,4,6-Triisopropylbenzenesulfonyl chloride Chemical Properties
Melting point 92-94 °C (lit.)
Boiling point 378C
density 1.1012 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility ethanol: 50 mg/mL, clear
form Crystalline Solid
color White to slightly beige
Water Solubility decomposes
Sensitive Moisture Sensitive
BRN 1218575
InChIKeyJAPYIBBSTJFDAK-UHFFFAOYSA-N
CAS DataBase Reference6553-96-4(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34-29
Safety Statements 26-36/37/39-45-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
21
Hazard Note Corrosive
HazardClass 8
PackingGroup II
HS Code 29049020
MSDS Information
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2,4,6-Triisopropylbenzenesulfonyl chloride English
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2,4,6-Triisopropylbenzenesulfonyl chloride Usage And Synthesis
Chemical PropertiesWhite to cream solid
Uses2,4,6-Triisopropylbenzenesulfonyl chloride is used for the synthesis of glycerophospholipids as a condensing agent and in the analysis of phosphonolipids in egg yolk by HPLC/MS technique. It acts as a coupling reagent for the synthesis of oligonucleotides and as sulfonates of pyrimidine nucleosides. It also serves as a condensing agent in the synthesis of hydrogen-phosphonate diesters.
Uses2,4,6-Triisopropylbenzenesulfonyl chloride can be used in the analysis of phosphonolipids in eggyolk by HPLC/MS technique.
It can also be used to synthesize:
  • Dimeric neomycin-neomycin conjugate with a flexible linker, 2,2′-(ethylenedioxy)bis(ethylamine).
  • Coupling reagents for the synthesis of oligonucleotides.
  • Sulfonates of pyrimidine nucleosides. These sulfonates can be displaced by nucleophiles in the presence of palladium-catalysts.
Methylene Chloride O-TOLUENESULFONYL CHLORIDE 2-Nitrobenzenesulfonyl chloride 1,3,5-TRIETHYLBENZENE 4-Ethylbenzene-1-sulfonyl chloride 2,4-Dimethylbenzenesulfonyl chloride Calcium chloride 2,4,6-TRIMETHYLTHIOPHENOL 1-ETHYL-3-ISO-PROPYLBENZENE Acetyl chloride 2,4,6-Triisopropylbenzenesulfonyl chloride Choline chloride Methanesulfonyl chloride Pivaloyl chloride Ammonium chloride 1,3,5-Triisopropylbenzene Potassium chloride (4-Isopropyl)thiophenol

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