2-Amino-3,5-dibromopyrazine

2-Amino-3,5-dibromopyrazine Basic information
Product Name:2-Amino-3,5-dibromopyrazine
Synonyms:2-AMINO-3,5-DIBROMOPYRAZINE;3,5-DIBROMOPYRAZIN-2-YLAMINE;3,5-DIBROMOPYRAZINE-2-YLAMINE;3,5-DIBROMOPYRAZIN-2-AMINE;2-AMINO-3,5-DIBROMOPYRAZIN;3,5-dibromo-2-Pyrazinamine;3,5-dibromo-2-aminopyrazine;2-Amino-3,5-dibromopyrazine ,98%
CAS:24241-18-7
MF:C4H3Br2N3
MW:252.89
EINECS:
Product Categories:Chloropyrazines, etc.;Pyrazine;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PyrazinesHeterocyclic Building Blocks;pharmacetical;Pyrazines;amine| alkyl bromide
Mol File:24241-18-7.mol
2-Amino-3,5-dibromopyrazine Structure
2-Amino-3,5-dibromopyrazine Chemical Properties
Melting point 114-117 °C (lit.)
Boiling point 294.6±35.0 °C(Predicted)
density 2.287±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility soluble in Methanol
pka0.81±0.10(Predicted)
form Powder
color Yellow to brown
InChIKeyDTLBKXRFWUERQN-UHFFFAOYSA-N
CAS DataBase Reference24241-18-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-37/38-41
Safety Statements 26-36/39
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Amino-3,5-dibromopyrazine Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
Uses2-Amino-3,5-dibromopyrazine is used in the preparation of conjugated polymers for neurotoxin detection. 2-Amino-3,5-dibromopyrazine is an intermediate in the preparation of rho kinase (ROCK) inhibitor s.
Uses2-Amino-3,5-dibromopyrazine may be used in the synthesis of:
  • 2-amino-5-bromopyrazin-3-thiol
  • 2-amino-3,5-bis(p-methoxyphenyl)-1,4-pyrazine
  • 3,7-dihydroimidazo[1,2a]pyrazine-3-ones
General Description2-Amino-3,5-dibromopyrazine can be synthesized from 2-aminopyrazine via bromination using N-bromosuccinimide (NBS). It reacts with sodium dicyanocuprate to form a mixture of mono and dicyanation products. The formation of 2-aminothiazolopyrazines by reacting 2-amino-3,5-dibromopyrazine with isothiocyanates has been reported.
2-Amino-3,5-dibromopyrazine Preparation Products And Raw materials
Preparation Products2-Amino-5-bromopyrazine-->Aminopyrazine-->6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE-->5-BROMO-PYRAZINE-2,3-DIAMINE-->2-AMINO-5-BROMO-3-ETHOXYPYRAZINE-->5-BroMo-3-(4-fluoro-phenyl)-pyrazin-2-ylaMine-->3-AMINO-6-BROMO-1H-PYRAZINE-2-THIONE
Pyrazine Aminopyrazine ALTRENOGEST 3,5-DIBROMO-6-CHLOROPYRAZIN-2-AMINE 6-Aminocaproic acid 2-Amino-3,5-dibromopyrazine Glycine 3,5-DIBROMO-6-(4-FLUOROPHENYL)-N-METHYLPYRAZIN-2-AMINE 3,5-DIBROMO-N,N-DIMETHYLPYRAZINAMINE Pyrazinamide Tris(hydroxymethyl)aminomethane Sulfachoropyrazine sodium AMINO ACIDS 2-AMINO-3,5-DIBROMO-6-METHYLPYRAZINE 3-Aminophenol 3,5-DIBROMO-6-[4-(TRIFLUOROMETHYL)PHENYL]PYRAZIN-2-AMINE Glipizide

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