ChemicalBook Product Catalog Organic Chemistry Amides Acyclic polyamines and their derivatives 1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE

1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE

1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE Basic information
Product Name:1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE
Synonyms:1,10-PHENANTHROLINE HYDROCHLORIDE;1,10-PHENANTHROLINE CHLORIDE MONOHYDRATE;1,10-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE;1,10-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE (O-);1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE;1,10-Phenanthroline monohydrochloride monohydrate 97%;1,10-Phenanthroline hydrochloride hydrate (1:1:1);O-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE
CAS:18851-33-7
MF:C12H11ClN2O
MW:234.68
EINECS:627-064-8
Product Categories:Amine Salts;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Antibiotics;Antibiotics A to Z;Antibiotics N-S;Heterocyclic Building Blocks;N-Containing;Others
Mol File:18851-33-7.mol
1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE Structure
1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE Chemical Properties
Melting point 224-225 °C(lit.)
storage temp. Inert atmosphere,Room Temperature
solubility H2O: 0.1 g/mL, clear
form Solid
color Colorless crystals
Water Solubility Soluble in water.
BRN 4007967
Stability:Stable for 2 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Safety Information
Hazard Codes T,N
Risk Statements 25-50/53
Safety Statements 45-60-61
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
F 8
TSCA Yes
HS Code 2933 99 80
HazardClass 6.1
PackingGroup III
ToxicityLD50 orally in Rabbit: 132 mg/kg
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE Usage And Synthesis
Description1,10-Phenanthroline (18851-33-7) is a high affinity chelator of divalent metal ions and may be used to inhibit zinc metalloenzymes.1? It is a potent inhibitor of JAMM-type isopeptidases (DUBs) acting via chelation of an active site Zn2+.? It may be used when preparing cell lysates for enrichment of ubiquitinated proteins? which are especially sensitive to DUBs in the JAMM family.2,3
Chemical PropertiesWhite fine crystalline powder
Uses1,10-Phenanthroline monohydrochloride monohydrate is used as an analytical reagent for colorimetric determination of iron.
References1) Swann?et al?(1981)?Zinc metalloenzyme properties of active and latent collagenase from rabbit bone;. Biochem.J.,?195?41 2) Cooper?et al. (2009) K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1; EMBO J.,?28?621 3) Lu?et al. (2015)?Substrate degradation by the proteasome: A single-molecule kinetic analysis; Science,?348?200
1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE Preparation Products And Raw materials
ZPCK o-Phenanthroline 4,7-DIHYDROXY-1,10-PHENANTHROLINE HYDROCHLORIDE PHENANTHROLINE RUTHENIUM DICHLORIDE, HYDRATE (1,10-PHENANTHROLINE)BIS(TRIPHENYLPHOSPHINE)COPPER (I) NITRATE DICHLOROMETHANE ADDUCT 2,9-DIMETHYL-1,10-PHENANTHROLINE HYDROCHLORIDE HYDRATE,2,9-DIMETHYL-1,10-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE,2,9-DIMETHYL-1,10-PHENANTHROLINE HYDROCHLORIDE 1,10-PHENANTHROLINE IRON(II) PERCHLORATE 5-METHYL-1,10-PHENANTHROLINE FERROUS PERCHLORATE 1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE 2,9-DIMETHYL-1,10-PHENANTHROLINE HYDROCHLORIDE DICHLOROTRIS(1,10-PHENANTHROLINE)RUTHENIUM(II) HYDRATE TRIS(4 7-DIPHENYL-1 10-PHENANTHROLINE)RU 1,10-PHENANTHROLINE HYDROCHLORIDE 5-NITRO-1,10-PHENANTHROLINE FERROUS PERCHLORATE 1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE P.A. 2,9-DIMETHYL-1,10-PHENANTHROLINE HYDROCHLORIDE DELTA-(-)-D-TRIS(1,10-PHENAN- THROLINE)RUTHENIUM(II) DIPERCHLORATE NEOCUPROINE HYDROCHLORIDE HYDRATE 98
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