FMOC-12-AMINODODECANOIC ACID

FMOC-12-AMINODODECANOIC ACID Basic information

Product Name:	FMOC-12-AMINODODECANOIC ACID
Synonyms:	N-(9-FLUORENYLMETHOXYCARBONYL)-12-AMINODODECANOIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-12-AMINOLAURIC ACID;N-(9-FLUORENYLMETHYLOXYCARBONYL)-12-AMINO-DODECANOIC ACID;FMOC-12-ADO-OH;FMOC-12-AMINODODECANOIC ACID;FMOC-12-AMINOLAURIC ACID;FMOC-NH-(CH2)11-COOH;12-(FMOC-AMINO)DODECANOIC ACID
CAS:	128917-74-8
MF:	C27H35NO4
MW:	437.57
EINECS:
Product Categories:	Amino Acids
Mol File:	128917-74-8.mol

FMOC-12-AMINODODECANOIC ACID Chemical Properties

Safety Information

Safety Statements	22-24/25
WGK Germany	3

MSDS Information

FMOC-12-AMINODODECANOIC ACID Usage And Synthesis

Description	Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical Properties	White to off-white powder
Uses	12-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)dodecanoic Acid has been used as a reactant for the preparation of pro-apoptotic peptide functionalized gold nanoparticles as a new anti-cancer strategy of damaging mitochondria.

FMOC-12-AMINODODECANOIC ACID Preparation Products And Raw materials

Raw materials

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