1-METHYLADENOSINE

1-METHYLADENOSINE Basic information
Product Name:1-METHYLADENOSINE
Synonyms:N,6-Didehydro-1,6-dihydro-1-methyladenosine;1-METHYLADENOSINE;1-methyladenosine free base;(2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol;(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;Adenosine, 1-methyl-;N1-Me-Adenosine;N1-Me-rA
CAS:15763-06-1
MF:C11H15N5O4
MW:281.27
EINECS:
Product Categories:Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
Mol File:15763-06-1.mol
1-METHYLADENOSINE Structure
1-METHYLADENOSINE Chemical Properties
Melting point >217°C (dec.)
Boiling point 655.4±65.0 °C(Predicted)
density 1.88±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO (Slightly), Water (Slightly, Sonicated)
pka13.24±0.70(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic, Light Sensitive
Safety Information
Safety Statements 24/25
HS Code 29389090
MSDS Information
1-METHYLADENOSINE Usage And Synthesis
Description1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.
Chemical PropertiesWhite to off-white crystalline powder
Uses1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.
DefinitionChEBI: A methyladenosine carrying a methyl substituent at position 1.
1-METHYLADENOSINE Preparation Products And Raw materials
2-AMINO-5'-O-(DIMETHOXYTRITYL)-N6-(DIMETHYLAMINOMETHYLIDENE)-N2-(ISOBUTYRYL)-2'-O-METHYLADENOSINE 8-(4-Chlorophenylthio)-2μ-O-methyladenosine 3μ,5μ-cyclic monophosphate hydrate monosodium 3'-O-[5'-Guanosyl(methyl)phosphono]-2'-O-methyladenosine 2'-O-METHYLADENOSINE-5'-TRIPHOSPHATE LITHIUM SALT 8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT N1-METHYLADENOSINE HYDROIODIDE 8-methyladenosine 2-(1-Hexynyl)-N6-methyladenosine,2-(1-HEXYNYL)-N-METHYLADENOSINE 8-(4-CHLOROPHENYLTHIO)-2'-METHYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE 8-AMINO-CADP-RIBOSE 1-METHYLADENOSINE N6-methyladenosine 5'-monophosphate*sodium,N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT 2-methyladenosine 6-methyladenosine (1-Methyl-1H-imidazol-4-yl)methylamine 2-AMINO-N2-ISOBUTYRYL-2'-O-METHYLADENOSINE 2',3'-Dideoxy-N-methyladenosine 3'-O-METHYLADENOSINE-5'-TRIPHOSPHATE LITHIUM SALT

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