Quinine hydrochloride dihydrate

Quinine hydrochloride dihydrate Basic information
Product Name:Quinine hydrochloride dihydrate
Synonyms:(R)(6-methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol monohydrochloride dihydrate;Cinchonan-9-ol, 6-methoxy-, monohydrochloride, dihydrate, (8.alpha.,9R)-;QUININEHYDROCHLORIDE,DIHYDRATE,CRYSTAL;Quinine Monohy;Quinine HCl Dihydrate;(8α,9R)-6'-methoxy-cinchonan-9-ol,hydrochloride, hydrate (1:1:2);(8α, 9R)-6′-Methoxycinchonan-9-ol monohydrochloride dihydrate;Quinine monohydrochloride dihydrate Vetec(TM) reagent grade, 88%
CAS:6119-47-7
MF:C20H27ClN2O3
MW:378.9
EINECS:612-097-2
Product Categories:API;Alkaloids;Biochemistry;for Resolution of Acids;Optical Resolution;Quinoline Alkaloids;Synthetic Organic Chemistry;AlkaloidAntibiotics;Antibiotics A to;Antibiotics N-SAntibiotics;Spectrum of Activity;Alphabetical Listings;Flavors and Fragrances;Q-Z;chiral;Antiparasitic / Antiprotozoal / AnthelminthicVoltage-gated Ion Channels;Biochemicals Found in Plants;Monovalent Ion Channels;Nutrition Research;Potassium Channel Modulators;Other APIs;Inhibitors;6119-47-7
Mol File:6119-47-7.mol
Quinine hydrochloride dihydrate Structure
Quinine hydrochloride dihydrate Chemical Properties
Melting point 115-116 °C (dec.)(lit.)
alpha [α]D20 -245~-255° (c=2, dil. HCl) (After Drying)
FEMA 2976 | QUININE HYDROCHLORIDE
refractive index -250 ° (C=2, EtOH)
Fp 122 °C
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility H2O: soluble0.25/5g/mL, clear, colorless
form Crystalline Powder or Silky Needles
color White to off-white
PH6.0 (10g/l, H2O, 20℃)
Odorodorless
Odor Typeodorless
optical activity[α]22/D 235°, c = 2 in 0.1 M HCl
Water Solubility Sparingly soluble in water.(0.26 g/L) (25°C),
Sensitive Light Sensitive
Merck 14,8061
BRN 6112655
InChIKeyMPQKYZPYCSTMEI-HPVDNOPASA-N
CAS DataBase Reference6119-47-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-42/43-36/37/38-20/21/22
Safety Statements 22-36/37-45-36/37/39-26-36
RIDADR 1544
WGK Germany 3
RTECS VA7700000
8
Hazard Note Irritant
HS Code 29392000
ToxicityLD50 orally in Rabbit: 620 mg/kg
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
Quinine hydrochloride dihydrate Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
UsesAntiprotozoal (malaria).
UsesQuinidine Hydrochloride Dihydrate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
Quinine hydrochloride dihydrate Preparation Products And Raw materials
DIPHENYLAMINE HYDROCHLORIDE Citric acid monohydrate Quinine sulfate dihydrate Topotecan hydrochloride 4-Methylpyridine Ethylenediamine dihydrochloride CINCHONIDINE SULFATE Quinine hydrochloride dihydrate DIETHANOLAMINE HYDROCHLORIDE QUININE SULFATE 3,3'-Dimethylbenzidine dihydrochloride Quinine hydochloride dihydrate CINCHONIDINE HYDROCHLORIDE QUINUCLIDINE HYDROCHLORIDE QUININE SULFATE SALT MONOHYDRATE METHANE FOROXYMITHINE Quinine

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