ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Proline derivatives Boc-L-beta-Homoproline

Boc-L-beta-Homoproline

Boc-L-beta-Homoproline Basic information
Product Name:Boc-L-beta-Homoproline
Synonyms:N-BOC-(2S)-PYRR(2-CHCOOH);N-BETA-T-BUTOXYCARBONYL-L-BETA-HOMOPROLINE;(S)-2-(1-BOC-2-PYRROLIDINYL)ACETIC ACID;(S)-N-T-BUTOXYCARBONYL-PYRROLIDINE-2-ACETIC ACID;BOC-L-BETA-HOMOPROLINE;BOC-BETA3-HOMOPRO;BOC-BETA-HOPRO-OH;BOC-BETA-HOMOPROLINE
CAS:56502-01-3
MF:C11H19NO4
MW:229.27
EINECS:
Product Categories:β-Homo Amino Acids;Beta amino acids
Mol File:56502-01-3.mol
Boc-L-beta-Homoproline Structure
Boc-L-beta-Homoproline Chemical Properties
Melting point 98 °C
Boiling point 357.4±15.0 °C(Predicted)
density 1.151±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka4.56±0.10(Predicted)
form Crystalline Powder
color White to off-white
BRN 478306
InChIKeyGDWKIRLZWQQMIE-QMMMGPOBSA-N
CAS DataBase Reference56502-01-3(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
Boc-L-beta-Homoproline Usage And Synthesis
UsesBuilding block for necine alkaloids.
UsesBoc-L-beta-homoproline is an amino acid derivative which is a reagent in the synthesis of dihydroisoxazole inhbitors of human transglutaminase 2, an enzyme that catalyzes the modification of glutamine residues. This enzyme has been implicated in numerous inflmmatory, fibrotic and other diseases.
(S)-(1-Boc-5-oxo-pyrrolidin-2-yl)acetic acid Povidone iodine N-Methyl-2-pyrrolidone (S)-2-(2-PYRROLIDINYL)ACETIC ACID Acetic anhydride Carbonyl iron powder Ascoric Acid N-Vinyl-2-pyrrolidone BOC-L-Proline Polyvinylpyrrolidone 3-TERT-BUTOXYCARBONYLAMINO-HEXANOIC ACID 2-tert-Butyl 6-methyl 4-bromo-3-oxo-2-azabicyclo[3.1.0]hex-3-ene-2,6-dicarboxylate Boc-L-beta-Homoproline tert-Butanol METHYL-2-PYRROLIDONE BOC-O-BENZYL-L-BETA-HOMOHYDROXYPROLINE DICYCLOHEXYLAMINE SALT L-PROLINE-(4-3H(N)) Phenylacetic acid
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