2',5'-Dimethoxyacetophenone

2',5'-Dimethoxyacetophenone Basic information
Product Name:2',5'-Dimethoxyacetophenone
Synonyms:Methyl 2,5-dimethoxyphenyl ketone;2,5-Dimethoxy acetonphenone;2',5'-Dimethoxyacetophenone,99%;2',5'-Dimethoxyaceto;1-(2,5-dimethoxyphenyl)-ethanon;Acetophenone, 2',5'-dimethoxy-;AKOS BBS-00004326;1-(2,5-dimethoxyphenyl)-ethanone
CAS:1201-38-3
MF:C10H12O3
MW:180.2
EINECS:214-858-0
Product Categories:Aromatic Acetophenones & Derivatives (substituted);C10;Carbonyl Compounds;Ketones;Acetophenone series;1201-38-3
Mol File:1201-38-3.mol
2',5'-Dimethoxyacetophenone Structure
2',5'-Dimethoxyacetophenone Chemical Properties
Melting point 18-20 °C(lit.)
Boiling point 155-158 °C11 mm Hg(lit.)
density 1.139 g/mL at 25 °C(lit.)
refractive index n20/D 1.5441(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Methanol (Slightly)
form Liquid
color Clear yellow to green-yellow
BRN 2047423
InChIKeyFAXUIYJKGGUCBO-UHFFFAOYSA-N
LogP2.125 (est)
CAS DataBase Reference1201-38-3(CAS DataBase Reference)
NIST Chemistry ReferenceEthanone, 1-(2,5-dimethoxyphenyl)-(1201-38-3)
EPA Substance Registry SystemEthanone, 1-(2,5-dimethoxyphenyl)- (1201-38-3)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
TSCA Yes
HazardClass IRRITANT
HS Code 29145090
MSDS Information
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2',5'-Dimethoxyacetophenone English
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2',5'-Dimethoxyacetophenone Usage And Synthesis
Chemical Propertiesclear yellow to green-yellow liquid
Uses2'',5''-Dimethoxyacetophenone is a useful building block which has been used in the preparation of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors, and in the synthesis of anti-cancer and apoptosis-inducing agents.
PreparationObtained by reaction of dimethyl sulfate with quinacetophenone in the presence of 10% aqueous sodium hydroxide.
2',5'-Dimethoxyacetophenone Preparation Products And Raw materials
Preparation Products(2,5-Dimethoxyphenyl)acetic acid-->2-Propen-1-one, 3-(4-chlorophenyl)-1-(2,5-dimethoxyphenyl)--->1-(2,5-DIMETHOXY-PHENYL)-ETHYLAMINE-->(2E)-3-(3-chlorophenyl)-1-(2,5-dimethoxyphenyl)prop-2-en-1-one-->3-( 2,5-dimethowy-phenyl)-3-oxo-propionic acid ethyl ester-->Benzenemethanamine, 2,5-dimethoxy-α-methyl-, (αS)-
2',4',5'-TRIMETHOXYACETOPHENONE 6-HYDROXY-2,4-DIMETHOXYACETOPHENONE,2-HYDROXY-4,6-DIMETHOXYACETOPHENONE,2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE MELICOPIDINE 2-(2-THIENYLIDENE)-3,4-DIMETHOXYACETOPHENONE 2-BROMO-2',5'-DIMETHOXYACETOPHENONE,A-BROMO-2',5'-DIMETHOXYACETOPHENONE Tangeretin 3'-BENZYLOXY-4',5,6,7-TETRAMETHOXYFLAVONE SCUTELLAREIN TETRAMETHYL ETHER hortensin 2'-HYDROXY-4',5'-DIMETHOXYACETOPHENONE 4'-Methyl-α,α-dimethoxyacetophenone Glycitein 2',3',4',6'-TETRAMETHOXYACETOPHENONE 6,7-DIMETHOXY-2,2-DIMETHYL-4-CHLOROMANONE 4',6,7-Trimethoxyisoflavone 3',4',5',6,7,8-HEXAMETHOXY-5-HYDROXYFLAVONE EUPATORIN-5-METHYL ETHER 1,2,3,4-TETRAMETHOXY-10-METHYLACRIDONE

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