Clodinafop-propargyl

Clodinafop-propargyl Basic information
Product Name:Clodinafop-propargyl
Synonyms:propynyl (r)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy] phenoxy]propanoate;CLODINAFOP-PROPARGYL;cga-184927;CLODINAFOP-PROPARGYL PESTANAL;Propanoic acid, 2-4-(5-chloro-3-fluoro-2-pyridinyl)oxyphenoxy-, 2-propynyl ester, (2R)-;clodinafop-propargyl ester (bsi, pa e-iso);Clodinafopacid;(R)-2-[4-[(5-Chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propionic acid 2-propynyl ester
CAS:105512-06-9
MF:C17H13ClFNO4
MW:349.74
EINECS:
Product Categories:Agro-Products;Aromatics;Chiral Reagents;Heterocycles;Alpha sort;C;CAlphabetic;CI - CLPesticides&Metabolites;Herbicides;Pesticides&Metabolites;Phenoxy structure
Mol File:105512-06-9.mol
Clodinafop-propargyl Structure
Clodinafop-propargyl Chemical Properties
Melting point 48-57°C
alpha D20 +45.4° (c = 2 in acetone)
Boiling point 432.7±45.0 °C(Predicted)
density 1.37 g/cm3(Temp: 22 °C)
storage temp. 0-6°C
solubility DMSO: 100 mg/mL (285.93 mM)
pka-1.54±0.32(Predicted)
form neat
BRN 8857008
CAS DataBase Reference105512-06-9(CAS DataBase Reference)
EPA Substance Registry SystemPropanoic acid, 2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]-, 2-propynyl ester, (2R)- (105512-06-9)
Safety Information
Hazard Codes Xn;N,N,Xn
Risk Statements 20/22-43-50/53-48/22
Safety Statements 36/37-60-61-46-24
RIDADR UN 2811
WGK Germany 3
HS Code 29333990
Hazardous Substances Data105512-06-9(Hazardous Substances Data)
ToxicityLD50 in rats (mg/kg): 1829 orally; >2000 dermally; LC50 in rats (4 hr): >2325 mg/m3 by inhalation (Amrein)
MSDS Information
ProviderLanguage
Clodinafop-propargyl English
Clodinafop-propargyl Usage And Synthesis
DescriptionClodinafop-propargyl is a foliar-absorbed aryloxyphenoxypropionate herbicide which has the capacity to inhibit the lipid biosynthesizing enzyme, acetyl coenzyme-A-carboxylase.
Clodinafop-propargyl is a member of the Oxyphenoxy acid ester chemical class, which includes the active ingredients fluazifop-butyl, fenoxaprop-ethyl, diclofop methyl, quizalofop-ethyl and haloxyfop-methyl.
Chemical PropertiesPure Clodinafop-propargyl is colorless crystal, vapor pressure (25℃)3.19×10-3mPa, Solubility (25℃): water 4.0mg/L, ethyl alcohol 97 mg/L, acetone 880 mg/L, methyl benzene 690mg/L, n-hexane 0.0086 mg/L. Distribution coefficient (octane/water): KOWlogP=3.9(25℃). Clodinafop-propargyl can inhibit the synthesis of ester-like biology. It can be used to control amur foxtail, oat grass, avena sterilis, green bristlegrass and other weeds.
UsesClodinafop-propargyl is a member of the aryloxyphenoxy propionate chemical family. It acts as a systemic herbicide that acts on post-emergent weeds such as selected grasses. It does not act on broad leaved weeds. It is applied to the foliar parts of the weeds and is absorbed through the leaves. This foliar acting grass weed killer is translocated to the meristematic growing points of the plant where it interferes with the production of fatty acids required for plant growth.Grass weeds controlled include wild oats, rough meadow-grass, green foxtail, barnyard grass, Persian darnel, volunteer canary seed. It also provides moderate control of Italian rye-grass. It is suitable for use on the following crops – all varieties of wheat, autumn-sown spring wheat, rye, triticale and durum wheat.
UsesHerbicides for weed control in wheat.
DefinitionChEBI: A carboxylic ester resulting from the formal condensation of the carboxy group of clodinafop with the hydroxy group of prop-2-yn-1-ol. It is widely used as a herbicide for the control of annual grass weeds in cereal crops.
Toxicity evaluationa) Mammalian toxicity : WHO Classification : Class III slightly hazardous”
b) Environmental toxicity : It is non-toxic to fish, birds and bees.
Shelf life :Two years under normal storage conditions (Tech grade and Formulation)
Mode of actionClodinafop-propargyl is to inhibit the activity of acetyl-CoA carboxylase in plants. It is a systemic conductive herbicide, absorbed by the leaves and sheaths of plants, transmitted by phloem, and accumulated in meristems of plants. In this case, acetyl-CoA carboxylase is inhibited, and fatty acid synthesis is stopped. So cell growth and division cannot proceed normally, and lipid-containing structures such as membrane systems are destroyed, leading to plant death.
Clodinafop-propargyl Preparation Products And Raw materials
CLODINAFOP-PROPARGYL SOLUTION 100UG/ML IN ACETONITRILE 1ML Cloransulam-methyl Cyhalofop-butyl CLODINAFOP 3-Bromopropyne CPPO A-NOR-5-ALPHA-ANDROSTAN-2-ALPHA, 17-ALPHA-DIETHYNYL-2-BETA, 17-BETA-DIOL DIPROPIONATE CLODINAFOP-PROPARGYL SOLUTION 100UG/ML IN TOLUENE 1ML FLUMIOXAZIN Clodinafop-propargyl propanoate PROPANOICACID,2-[4-[(5-CHLORO-3-FLUORO-2-PYRIDINYL)OXY]PHENOXY]-,2-PROPYNYLESTER Trimethoxysilylpropanethiol CLODINAFOP - PROPARGYL TECHNICAL / 15 WP Chromium picolinate 2-(4-Hydroxyphenoxy)propionic acid methyl ester Quizalofop-p-tefuryl 3-Chloropropyne

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