5-Hydroxyquinoline

5-Hydroxyquinoline Basic information

Product Name:	5-Hydroxyquinoline
Synonyms:	5-HYDROXYQUINOLINE;5-QUINOLINOL;TIMTEC-BB SBB004118;QUINOLIN-5-OL;5-QUINOLINOL 98+%;5-Hydroxyquinoline ,98%;5-Quinolinol,5-Hydroxyquinoline;1H-Quinolin-5-one
CAS:	578-67-6
MF:	C9H7NO
MW:	145.16
EINECS:	209-428-4
Product Categories:	Hydroxyquinolines;Quinolines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	578-67-6.mol

5-Hydroxyquinoline Chemical Properties

Melting point	223-226 °C(lit.)
Boiling point	264.27°C (rough estimate)
density	1.1555 (rough estimate)
refractive index	1.4500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO, Methanol
form	Solution
pka	pK1:5.20(＋1);pK2:8.54(0) (20°C)
color	Colorless to yellow, may darken during storage
Water Solubility	416.5mg/L(20 ºC)
BRN	114514
CAS DataBase Reference	578-67-6(CAS DataBase Reference)
NIST Chemistry Reference	5-Quinolinol(578-67-6)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	VC4100000
Hazard Note	Irritant
HS Code	29334900

MSDS Information

Provider	Language
5-Hydroxyquinoline	English
SigmaAldrich	English

5-Hydroxyquinoline Usage And Synthesis

Chemical Properties	White to beige crystalline powder
Uses	5-Quinolinol (5-Hydroxyquinoline) was used as an internal standard in the reaction to measure morphine concentration in serum or plasma. It was also used as a lipophilic chelator and it decreased the rate of deoxygenation.
Definition	ChEBI: Quinolin-5-ol is a monohydroxyquinoline.

5-Hydroxyquinoline Preparation Products And Raw materials

Raw materials	Acetic acid-->Sodium nitrite-->Iron-->Sodium bisulfite-->Stannous chloride dihydrate-->5-Nitroquinoline
Preparation Products	7-Hydroxyquinoline-->5-(oxiran-2-ylmethoxy)quinoline-->1-(5-Hydroxy-3,4-dihydroquinolin-1(2H)-yl)ethanone-->(R)-5-(oxiran-2-ylmethoxy)quinoline

5-METHOXYQUINOLIN-8-AMINE 4-CHLORO-5,6,7-TRIMETHOXYQUINOLINE 4-Hydroxyquinoline alpha-((Diethylamino)methyl)-p-((1-methoxy-6-nitro-9-acridinyl)amino)b enzyl alcohol SPECS AE-562/12222294 Iodure de diacetoxy-1,4 methoxy-2 methyl-10 acridinium [French] MS 073 5-Hydroxyquinoline 9-HYDROXYCAMPTOTHECIN, [12-3H(N)]- 2-Quinolinol SQI-PR 5-Quinolinol, 8-(9,10-dihydro-10-methyl-9-acridinyl)- 1,3-DIHYDROXY-9-ACRIDINECARBOXYLIC ACID ZOSUQUIDAR TRIHYSROCHLORIDE 6-Hydroxyquinoline 8-HYDROXYQUINOLINE BASE Quinhydrone 5,8-DIMETHOXYQUINOLINE

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