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| | Loxoprofen sodium Basic information |
| | Loxoprofen sodium Chemical Properties |
| storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO: soluble | | form | A solid | | InChI | InChI=1S/C15H18O3.Na.H/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);; | | InChIKey | ALZXNWUYLUBHJL-UHFFFAOYSA-N | | SMILES | C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1.[NaH] | | CAS DataBase Reference | 80382-23-6(CAS DataBase Reference) |
| | Loxoprofen sodium Usage And Synthesis |
| Description | Loxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity. | | Originator | Sankyo (Japan) | | Uses | anti-inflammatory | | Definition | ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration. | | Brand name | LOXONIN | | Mechanism of action | As most NSAIDs, loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. | | Side effects | Adverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation. |
| | Loxoprofen sodium Preparation Products And Raw materials |
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