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| | caudatin Basic information |
| Product Name: | caudatin | | Synonyms: | caudatin;(3beta,12beta,14beta,17alpha)-12-[[(2E)-3,4-Dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxypregn-5-en-20-one;Caudatin ,98%;Pregn-5-en-20-one,12-[[(2E)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxy-, (3b,12b,14b,17a)-;Pregn-5-en-20-one, 12-[[(2E)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxy-, (3β,12β,14β,17α)-;[(3S,8S,9R,10R,12R,13S,14R,17R)-17-acetyl-3,8,14,17-tetrahydroxy-10,13-dimethyl-1,2,3,4,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-12-yl] (E)-3,4-dimethylpent-2-enoate | | CAS: | 38395-02-7 | | MF: | C28H42O7 | | MW: | 490.63 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 38395-02-7.mol |  |
| | caudatin Chemical Properties |
| Boiling point | 617.9±55.0 °C(Predicted) | | density | 1.25 | | storage temp. | 4°C, protect from light | | solubility | DMF:30.0(Max Conc. mg/mL);61.15(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);61.15(Max Conc. mM)
Ethanol:30.0(Max Conc. mg/mL);61.15(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:7):0.12(Max Conc. mg/mL);0.24(Max Conc. mM) | | form | A solid | | pka | 11.93±0.70(Predicted) |
| | caudatin Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. | | Uses | Gaodatin has inhibitory effect on the growth of various human-derived tumor cell lines such as human gastric cancer, colon cancer, and lung cancer. | | Biological Activity | Caudatin, a C-21 steroid hormone derived from Cynanchum auriculatum (C. auriculatum), potently inhibits human glioma growth in vitro and in vivo by triggering cell cycle arrest and apoptosis. |
| | caudatin Preparation Products And Raw materials |
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