WILFORGINE

WILFORGINE Basic information
Uses Biological activity
Product Name:WILFORGINE
Synonyms:(8alpha)-8-(Acetyloxy)-O2-deacetyl-8-deoxo-O2-(3-furanylcarbonyl)- evonimine Wilforgin;WILFORGINE;Aids088959;Aids-088959;3-Furancarboxylic acid (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-yl ester;4-27-00-06847 (Beilstein Handbook Reference);3-Furancarboxylic acid (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-;3-Furancarboxylic acid, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-yl ester, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-
CAS:37239-47-7
MF:C41H47NO19
MW:857.81
EINECS:
Product Categories:CR;reagent;standard substance
Mol File:37239-47-7.mol
WILFORGINE Structure
WILFORGINE Chemical Properties
Melting point 211℃
Boiling point 859.9±65.0 °C(Predicted)
density 1.43
solubility Soluble in methanol;
pka11.59±0.70(Predicted)
form powder
color White
Water Solubility insoluble in water
Safety Information
MSDS Information
WILFORGINE Usage And Synthesis
UsesWilforgine can be used as lymphocyte immunosuppression, with anti-tumor and anti-inflammatory effects, and can be used for content determination/identification/pharmacological experiments, etc.
Biological activityWilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
DescriptionWilforgine is a alkaloid,it from Tripterygiurn wilfordii Hook forms colourless plates from MeOH-Me2CO. It is also dextrorotatory having [α]25/sup>D + 25° (Me2CO)
DefinitionChEBI: A dihydroagarofuran sesquiterpenoid and pyridine alkaloid with formula C41H47NO19 originally isolated from the roots of Tripterygium wilfordii.
ReferencesBeroza., J. Arner. Chern. Soc., 74, 1585 (1952) Beroza., ibid, 75,44 (1953)
WILFORGINE Preparation Products And Raw materials
Triptonide WILFORINE Triptolide Tripdiolide WILFORDINE wilfortrine Wilfornine A 2,2,5,5-TETRAMETHYLTETRAHYDROFURAN 2,6-Decahydronaphthalenediol TETRAHYDROFURFURYL NICOTINATE NICOTINIC ACID N-OCTYL ESTER WILFORGINE 4-(pyridin-2-yl)butanoic acid CIS-P-MENTHANE-3,8-DIOL BUTOXYETHYL NICOTINATE (1S)-(+)-NEOMENTHYL ACETATE Hexyl nicotinate (+/-)-GEOSMIN

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