ChemicalBook Product Catalog Chemical Reagents Organic reagents Tosylate Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate

Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate

Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Basic information
Product Name:Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate
Synonyms:Ethyl (R)-2-hydroxy-4-phenylbutyrate triflate;ethyl (r)-[alpha-(trifluoromethylsulfonyl)oxy]benzenebutanoate;(2R)-2-ethyl-2-hydroxy-4-phenylbutanoic acid;ethyl (r)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate;alpha-[[(Trifluoromethyl)sulfonyl]oxy]-benzenebutanoic acid ethyl ester;(R)-Ethyl-2-trifluoromethyl sulphonyloxy-4-phenyl butanoate;(R)-ethyl 4-phenyl-2-(trifluoromethylsulfonyloxy)butanoate;ethyl (2R)-4-phenyl-2-[(trifluoroMethane)sulfonyloxy]butanoate
CAS:88767-98-0
MF:C13H15F3O5S
MW:340.31
EINECS:1308068-626-2
Product Categories:API intermediates
Mol File:88767-98-0.mol
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Structure
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Chemical Properties
Boiling point 390.8±42.0 °C(Predicted)
density 1.348
refractive index 1.4520 to 1.4560
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Light yellow to Amber to Dark green
Safety Information
HS Code 2918.19.9000
MSDS Information
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Usage And Synthesis
UsesEthyl (R)?-?4-?Phenyl-?2-?[[(trifluoromethyl)?sulfonyl]?oxy]?butyrate is an intermediate in synthesizing Enalapril-d3 Hydrochloride (E555258), which is the hydrochloride salt of Enalapril-d3 (E555253), a labeled version of Enalapril (E555403), an antihypertensive that is also an angiotensin-converting enzyme (ACE) inhibitor.
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Preparation Products And Raw materials
Raw materialsEthyl (R)-2-hydroxy-4-phenylbutyrate-->3-Butenoic acid, 2-oxo-4-phenyl-, (E)--->(R)-2-Hydroxy-4-phenylbutyric acid-->Trifluoromethanesulfonic anhydride
Ethanol Ethyl formate Methanesulfonic acid Butyric Acid Tris(trimethylsilyl)phosphate Ethylbenzene Levofloxacin Methylate Ethylparaben CHLOROETHANE Trifluoromethyl Ethyl cellulose Diethyl ether Trifluoromethanesulfonic acid Ethyl acetate Triphenylphosphine oxide Ethyl acrylate CHLOROPHOSPHONAZO III Phenylhydrazine
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