ChemicalBook Product Catalog Organic Chemistry Amides S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide

S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide

S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide Basic information
Product Name:S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide
Synonyms:(S)-3-(DiMethylaMino)-1-(thiophen-3-yl)propan-1-ol;rac-α-[2-(Dimethylamino)ethyl]-3-thiophenemethanol;S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide;3-THIOPHENEMETHANOL, A-[2-(DIMETHYLAMINO)ETHYL]-;S-(-)-N,N-DIMETHYL-3-HYDROXY-2-THIENYLPROPANAMINE;S(+)-N,N-DIMETHYL-3-HYDROXY-3-(2-THIENYL)-1-PROPANAMINE;(S)-1-b-Hydroxy-1-(2-thienyl)-3-dimethylaminopropane;3-THIOPHENEMETHANOL, A-[2-(DIMETHYLAMINO)ETHYL]-(9CI)
CAS:116817-84-6
MF:C9H15NOS
MW:185.29
EINECS:
Product Categories:Pharmaceuticals;Sulfur & Selenium Compounds;Heterocycles;Intermediates & Fine Chemicals
Mol File:116817-84-6.mol
S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide Structure
S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide Chemical Properties
Melting point 74-76°C
Boiling point 290.1±30.0 °C(Predicted)
density 1.111±0.06 g/cm3(Predicted)
storage temp. Room Temperature, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka14.35±0.20(Predicted)
form Solid
color White to Off-White
CAS DataBase Reference116817-84-6(CAS DataBase Reference)
Safety Information
MSDS Information
S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide Usage And Synthesis
Chemical PropertiesWhite Crystalline Solid
UsesS-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide is a useful synthetic intermediate.
Usesrac-α-[2-(Dimethylamino)ethyl]-3-thiophenemethanol is an intermediate in the synthesis of rac Duloxetine 3-Thiophene Isomer (D721025). rac Duloxetine 3-Thiophene Isomer Hydrochloride is an isomeric impurity of the antidepressant Duloxetine Hydrochloride (D721000).
S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide Preparation Products And Raw materials
Duloxetine IMpurity A (S)-Duloxetine SuccinaMide 4-HYDROXY-4-(5-METHYL-2-THIENYL)-1-ISOPROPYLPIPERIDINE 4-HYDROXY-4-(2-THIENYL)-1-METHYLPIPERIDINE AKOS 94341 4-HYDROXY-4-(2-THIENYL)-1-ISOPROPYLPIPERIDINE 1-(2,5-DICHLORO-3-THIENYL)-3-(DIMETHYLAMINO)-1-PROPANOL 4-HYDROXY-4-(5-METHYL-2-THIENYL)-1-METHYLPIPERIDINE 4-(2-CHLORO-5-THIENYL)-4-HYDROXY-1-ISOPROPYLPIPERIDINE AKOS 91515 AKOS 91503 S-(+)-N,N-DIMETHYL-3-(1-NAPHTHLENYLOXY)-3-(2-THIENYL)-PROPANAMINE 4-(2-CHLORO-5-THIENYL)-4-HYDROXY-1-METHYLPIPERIDINE 3-THIOPHENEPROPANAMINE, N,N-DIMETHYL-GAMMA-(1-NAPHTHALENYLOXY)-, ETHANEDIOATE(1:1) S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide (R)-(+)- N,N-dimethyl-3-hydroxy-3-(2-thienyl)propanamine (RS)-N,N-DIMETHYL-3-HYDROXY-3-(2-THIENYL)PROPANAMINE AKOS 91648
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