4-Methoxyphenylacetone

4-Methoxyphenylacetone Basic information
Product Name:4-Methoxyphenylacetone
Synonyms:4-ANISYL ACETONE;4-METHOXYBENZYL METHYL KETONE;4-METHOXYPHENYLACETONE;4-ACETONYLANISOLE;1-(P-METHOXYPHENYL)-2-PROPANONE;3-(4-METHOXYPHENYL)-2-PROPANONE;1-(4-METHOXYPHENYL)-2-PROPANONE;P-METHOXYBENZYL METHYL KETONE
CAS:122-84-9
MF:C10H12O2
MW:164.2
EINECS:204-578-7
Product Categories:ketone;API intermediates;Aromatic Ketones (substituted);Aromatics;Miscellaneous Reagents;122-84-9
Mol File:122-84-9.mol
4-Methoxyphenylacetone Structure
4-Methoxyphenylacetone Chemical Properties
Melting point <-15 °C
Boiling point 145 °C/25 mmHg (lit.)
density 1.067 g/mL at 25 °C (lit.)
vapor pressure 1.37Pa at 25℃
FEMA 2674 | 1-(P-METHOXYPHENYL)-2-PROPANONE
refractive index n20/D 1.525(lit.)
Fp 215 °F
storage temp. Sealed in dry,Room Temperature
solubility Methyl Acetate: 50 mg/ml
form Liquid
color Clear light yellow to yellow-green
Odorat 10.00 % in dipropylene glycol. sweet fruity creamy spicy green anisic balsamic licorice fennel
Odor Typefruity
Water Solubility 3.084g/L at 25℃
JECFA Number813
BRN 2044332
InChIKeyWFWKNGZODAOLEO-UHFFFAOYSA-N
LogP1.55 at 25℃
CAS DataBase Reference122-84-9(CAS DataBase Reference)
NIST Chemistry Reference2-Propanone, 1-(4-methoxyphenyl)-(122-84-9)
EPA Substance Registry System2-Propanone, 1-(4-methoxyphenyl)- (122-84-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 23-24/25
WGK Germany 2
RTECS UC2990000
Hazard Note Irritant
TSCA Yes
HS Code 29145000
ToxicityLD50 orl-rat: 3330 mg/kg FCTXAV 17,857,79
MSDS Information
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4-Methoxyphenylacetone English
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4-Methoxyphenylacetone Usage And Synthesis
Descriptionl-(p-Methoxyphenyl)-2-propanone has an odor and taste similar to anise. May be obtained by boiling α- or β-anetholglycol with a 20% solution of sulfuric acid, or from l-(p-methoxyphenyl)- propan-l,2-ol by treatment with diluted sulfuric acid.
Chemical Properties1-(p-Methoxyphenyl)-2-propanone has an odor and taste similar to anise.
Chemical PropertiesPale Yellow Liquid
OccurrenceReported found in Chinese star anise and in Russian star anise; also reported found in sweet and common fen nel, chervil (Anthriscus cerefolium) and Illicium verum and cherry
UsesA volatile compound released by flowering plants to attractant insects
PreparationObtained by boiling α- or β-anetholglycol with a 2% solution of sulfuric acid, or from 1-(p-methoxyphenyl)-propan-1,2-ol by treatment with diluted sulfuric acid.
DefinitionChEBI: 1-(4-Methoxyphenyl)-2-propanone is an alkylbenzene.
Taste threshold valuesTaste characteristics at 15 ppm: sweet spicy, with green anisic, minty nuances.
Synthesis Reference(s)The Journal of Organic Chemistry, 61, p. 1748, 1996 DOI: 10.1021/jo9518314
General DescriptionAsymmetric amination of 4-methoxyphenylacetone was studied.
Flammability and ExplosibilityNotclassified
Safety ProfileModerately toxic by ingestion andother routes. A skin irritant. A flammable liquid.
4-Methoxyphenylacetone Preparation Products And Raw materials
Preparation Products4-METHOXY-BETA-BROMOPROPIOPHENONE-->N-ethyl-p-methoxy-alpha-methylphenethylamine-->(R)-2-(4-Methoxyphenyl)-1-methylethanamine-->4-Hydroxyphenylacetone-->(S)-2-(4-Methoxyphenyl)-1-MethylethanaMine-->5-Acetonyl-2-methoxybenzene sulfonamide-->5-ACETONYL-2-METHOXYBENZENESULPHONYLCHLORIDE
Methyl Citric acid monohydrate Parathion-methyl Phenylacetone 4-Methoxyphenylacetone 2-METHOXYPHENYLACETONE,2-Methoxyphenylacetone, 98+% 4-METHOXYPHENETHYL ALCOHOL Tribenuron methyl Kresoxim-methyl Methoxypropiophenone Thiophanate-methyl Methoxyacetone Methyl salicylate Methyl acetate Methyl bromide 4-Methoxyphenylhydrazine hydrochloride METSULFURON METHYL 4-Methoxybenzenesulfonyl chloride

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