4-Hydroxy-6-methylpyrimidine

4-Hydroxy-6-methylpyrimidine Basic information
Product Name:4-Hydroxy-6-methylpyrimidine
Synonyms:6-METHYL-PYRIMIDIN-4-OL;6-METHYL-4-PYRIMIDINOL;6-METHYL-4(3H)-PYRIMIDINONE;AKOS BC-0740;4-HYDROXY-6-METHYLPYRIMIDINE;4(1H)-Pyrimidinone, 6-methyl-;4-Pyrimidinol, 6-methyl-;6-methyl-4(1h)-pyrimidinon
CAS:3524-87-6
MF:C5H6N2O
MW:110.11
EINECS:222-543-4
Product Categories:Heterocycle-Pyrimidine series;Pyrimidine series;PYRIMIDINE;Pyridines, Pyrimidines, Purines and Pteredines
Mol File:3524-87-6.mol
4-Hydroxy-6-methylpyrimidine Structure
4-Hydroxy-6-methylpyrimidine Chemical Properties
Melting point 145-150℃
Boiling point 192.1±23.0 °C(Predicted)
density 1.22±0.1 g/cm3(Predicted)
RTECS UW7528000
storage temp. Sealed in dry,Room Temperature
pka9.46±0.40(Predicted)
form Solid
color White to brown
InChIKeyLHRIUKSRPHFASO-UHFFFAOYSA-N
NIST Chemistry Reference6-Methyl-4-pyrimidinol(3524-87-6)
EPA Substance Registry System6-Methyl-4(1H)-pyrimidinone (3524-87-6)
Safety Information
Hazard Codes Xn
Risk Statements 22-41
Safety Statements 26-39
WGK Germany 3
TSCA Yes
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
4-Hydroxy-6-methylpyrimidine Usage And Synthesis
Uses6-Methyl-4-hydroxypyrimidine is used in the preparation of antitumor compounds based upon adenine. Also used in the synthesis of novel purimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide derrivatives as tyrosine kinase inhibitors.
4-Hydroxy-6-methylpyrimidine Preparation Products And Raw materials
Raw materialsMethylthiouracil-->6-Methyluracil
Preparation Products5-IODO-6-METHYL-4-PYRIMIDINAMINE-->5-BROMO-4-CHLORO-6-METHYLPYRIMIDINE-->4(1H)-Pyrimidinethione, 6-methyl- (9CI)-->5-IODO-6-METHYLPYRIMIDIN-4-OL
Methylparaben Sulfamerazine Methyl Acetonitrile 2,6-Dimethylphenol Sulfadiazine 4-Hydroxy-6-methylpyrimidine 4-Hydroxypyrimidine Basic Violet 1 Kresoxim-methyl 2-ISOPROPYL-4-HYDROXY-6-METHYLPYRIMIDINE 2,6-Lutidine Pirimiphos-methyl Methanol Methyl acrylate Methyl acetate Methyl bromide CHLOROPHOSPHONAZO III

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