5-(Trifluoromethyl)pyridine-2-carboxylic acid

5-(Trifluoromethyl)pyridine-2-carboxylic acid Basic information

Product Name:	5-(Trifluoromethyl)pyridine-2-carboxylic acid
Synonyms:	5-(TRIFLUOROMETHYL)PICOLINIC ACID;5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID;5-TRIFLUOROMETHYL-2-PYRIDINECARBOXYLIC ACID;5-Trifluoromethyl-2-Pyridineca;5-(Trifluoromethyl)pyridine-2-carboxylic acid 97%;5-(Trifluoromethyl)pyridine-2-carboxylicacid97%;5-trifluoro-2-pyridinecarboxylic acid;5-(Trifluoromethyl)picolinic acid, 2-Carboxy-5-(trifluoromethyl)pyridine
CAS:	80194-69-0
MF:	C7H4F3NO2
MW:	191.11
EINECS:
Product Categories:	Carboxylic Acids;Pyridines;Carboxylic Acids;Fluorine series
Mol File:	80194-69-0.mol

5-(Trifluoromethyl)pyridine-2-carboxylic acid Chemical Properties

Melting point	135-137°C
Boiling point	273.7±40.0 °C(Predicted)
density	1.484±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.13±0.10(Predicted)
form	Powder
color	Pale brown
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	80194-69-0(CAS DataBase Reference)

Safety Information

MSDS Information

5-(Trifluoromethyl)pyridine-2-carboxylic acid Usage And Synthesis

Uses	5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.
Uses	5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.

5-(Trifluoromethyl)pyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials	Ethyl acetate-->Diethyl ether-->Tetrahydrofuran-->N,N-Dimethylformamide-->Toluene-->n-Butyllithium-->Hexane-->Nitrogen-->CARBON DIOXIDE-->Iodine-->N-Methyl-2-pyrrolidone-->(Trifluoromethyl)trimethylsilane-->2,5-Dibromopyridine-->2-Bromo-5-(trifluoromethyl)pyridine-->2-Iodo-5-trifluoromethylpyridine-->(5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-ACETONITRILE
Preparation Products	5-TRIFLUOROMETHYL-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER

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