RHAPONTIN

RHAPONTIN Basic information
Product Name:RHAPONTIN
Synonyms:3,3',5-TRIHYDROXY-4'-METHOXY-STILBENE 3-O-BETA-D-GLUCOSIDE;4'-METHOXY-3,3',5-STILBENETRIOL-3-GLUCOSIDE;4'-METHOXY-3,3',5-STILBENETROL;3-hydroxy-5-[2-(3-hydroxy-4-methoxyphenyl)vinyl]phenyl-beta-D-glucopyranoside;RHAPONTICIN;RHAPONTIN;RHAPONTIN FROM RHUBARB ROOT;RHAPONTIN WITH HPLC
CAS:155-58-8
MF:C21H24O9
MW:420.41
EINECS:205-845-0
Product Categories:Miscellaneous Natural Products;Cardioglycosides & Glycosides
Mol File:155-58-8.mol
RHAPONTIN Structure
RHAPONTIN Chemical Properties
Melting point 236-240 °C
alpha D32 -59.5° (acetone)
Boiling point 457.61°C (rough estimate)
density 1.2828 (rough estimate)
refractive index 1.6230 (estimate)
storage temp. 2-8°C
solubility Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
form neat
pka9.16±0.10(Predicted)
color Brown
Water Solubility slightly soluble in water
Merck 13,8258
Stability:Hygroscopic
InChIKeyGKAJCVFOJGXVIA-DXKBKAGUSA-N
LogP0.680 (est)
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 24/25-37/39-26
WGK Germany 3
HS Code 29389090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
RHAPONTIN Usage And Synthesis
Chemical Propertieslight beige powder
UsesRhapontin is a stilbene derivative found in Rheum. It is an inhibitor of Tyrosinase which is responsible for the molting process in insects, undesirable browning of fruits and vegetables, and coloring of skin, hair, and eyes in animals.
DefinitionChEBI: Trans-rhaponticin is a rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities. It has a role as an anti-inflammatory agent, a plant metabolite, a neuroprotective agent, an EC 2.3.1.85 (fatty acid synthase) inhibitor, an antineoplastic agent, an apoptosis inducer, an angiogenesis inhibitor, a hypoglycemic agent, an anti-allergic agent and an antilipemic drug.
targetLDL
RHAPONTIN Preparation Products And Raw materials
METHYL 6-DEOXY-BETA-D-GLUCOPYRANOSIDE 2-(3-METHYLPHENOXY)ETHANOL 1-PHENOXY-2-PROPANOL PINOSYLVIN 2-PHENOXYTETRAHYDROPYRAN 3-Phenoxy-1,2-propanediol 1-(3-METHYLPHENOXY)-2-PROPANOL DEXTROSE RHAPONTIN Polydatin PINOSYLVIN MONO METHYL ETHER METHYL-BETA-D-XYLOPYRANOSIDE 3-Butoxyphenol O-HYDROXYETHYLRESORCINOL trans-3-HYDROXYSTILBENE 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE PICEATANNOL PHENYL-BETA-D-GLUCOPYRANOSIDE

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