trans-3,4-Difluorocinnamic acid

trans-3,4-Difluorocinnamic acid Basic information

Product Name:	trans-3,4-Difluorocinnamic acid
Synonyms:	(E)-3,4-Difluorophenylacrylic acid, (2E)-3-(3,4-Difluorophenyl)prop-2-enoic acid;3,4-DIFLUOROCINNAMIC ACID;AKOS 92715;TIMTEC-BB SBB006677;RARECHEM BK HW 0122;TRANS-3,4-DIFLUOROCINNAMIC ACID;trans-3,4-Difluorocinnamic acid 97%;trans-3,4-Difluorocinnamicacid97%
CAS:	112897-97-9
MF:	C9H6F2O2
MW:	184.14
EINECS:
Product Categories:	Aromatic Cinnamic Acids, Esters and Derivatives;Cinnamic acid;Miscellaneous;C9;Carbonyl Compounds;Carboxylic Acids;Fluoro-contained cinnamic acid series
Mol File:	112897-97-9.mol

trans-3,4-Difluorocinnamic acid Chemical Properties

Safety Information

MSDS Information

trans-3,4-Difluorocinnamic acid Usage And Synthesis

Chemical Properties	white to light yellow crystal powder
Uses	trans-3,4-Difluorocinnamic Acid is a starting material in the preparation of Ticagrelor (T437700), which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.

trans-3,4-Difluorocinnamic acid Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Ethyl acetate-->Diethyl ether-->Dichloromethane-->Magnesium sulfate-->Sodium bicarbonate-->Hexane-->Triphenylphosphine-->tert-Butyl bromoacetate-->Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester-->3,4-Difluorobenzaldehyde
Preparation Products	(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid-->(E)-Methyl 3-(3,4-difluorophenyl)acrylate-->Benzene, 1,2-difluoro-4-[(1E)-2-isocyanatoethenyl]-

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