2-Amino-1-(2,5-dimethoxyphenyl)ethanol

2-Amino-1-(2,5-dimethoxyphenyl)ethanol Basic information
Product Name:2-Amino-1-(2,5-dimethoxyphenyl)ethanol
Synonyms:1-methoxy-2-(3-methoxyanilino)ethanol;Midodrine Hydrochloride Impurit Ⅰ:2-Amino-1-(2,5-dimethoxyphenyl)ethanol;Benzenemethanol, a-(aminomethyl)-2,5-dimethoxy-;DE-GLYMIDODRINE;DESGLYMIDODRINE;1-(2',5'-DIMETHOXYPHENYL)-2-AMINOETHANOL;2-AMINO-1-(2,5-DIMETHOXY-PHENYL)-ETHANOL;Midodrine Related CoMpound A
CAS:3600-87-1
MF:C10H15NO3
MW:197.23
EINECS:868-039-3
Product Categories:Metabolites;1
Mol File:3600-87-1.mol
2-Amino-1-(2,5-dimethoxyphenyl)ethanol Structure
2-Amino-1-(2,5-dimethoxyphenyl)ethanol Chemical Properties
Melting point 146-150°C dec.
Boiling point 364.3±42.0 °C(Predicted)
density 1.145±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly, Sonicated), Methanol (Slightly)
pka11.84±0.35(Predicted)
form Solid
color White to Off-White
Safety Information
HS Code 2922199695
MSDS Information
ProviderLanguage
ALFA English
2-Amino-1-(2,5-dimethoxyphenyl)ethanol Usage And Synthesis
Chemical PropertiesWhite Powder
UsesA metabolite of Midodrine. It induces alpha-adrenergic receptor stimulation of both arterial and venous systems without direct central nervous systme of cardiac effects. Midodrine Related Compound A
DefinitionChEBI: An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-amino-1-hydroxyethyl group. The immediate and active metabolite of midrodine, it is a direct-acting sympathomimetic with selective alpha-adrenergic agon st activity. Midrodine is used (generally as its hydrochloride salt) as a prodrug for deglymidodrine, which acts as a peripheral vasoconstrictor in the treatment of certain hypotensive states.
2-Amino-1-(2,5-dimethoxyphenyl)ethanol Preparation Products And Raw materials
Raw materialsBenzeneacetonitrile, α-hydroxy-2,5-dimethoxy--->1-(2,5-Dimethoxyphenyl)-2-nitroethanol-->2-BROMO-2',5'-DIMETHOXYACETOPHENONE-->2,5-Dimethoxybenzaldehyde
isopropylmethoxamine Monoethanolamine Ethanol Dimethyldimethoxysilane 4-Dimethylaminobenzoic acid ALTRENOGEST 2-Amino-1-(2,5-dimethoxyphenyl)ethanol 4-Dimethylaminobenzaldehyde 2-Methoxyethanol Glycine Diethylaminoethanol Butoxamin 2-Dimethylaminoethanol Ethyl acetate AMINO ACIDS 2,5-DIMETHOXYPHENYLNITROETHANOL 4-Dimethylaminopyridine 2-Phenoxyethanol

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