(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL

(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Basic information

Product Name:	(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL
Synonyms:	(S)-(+)-2,2,2-TRIFLUORO-1-PHENYLETHANOL;(S)-2,2,2-TRIFLUORO-1-PHENYL-ETHANOL;(S)-(+)-1-PHENYL-2,2,2-TRIFLUOROETHANOL;(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL;(+)-PHENYL(TRIFLUOROMETHYL)CARBINOL;(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL AL COHOL, 99% (97% EE/GLC);(s)-(+)-α-(trifluoromethyl)benzyl alcohol;(+)-Phenyl(trifluoromethyl)carbinol, (S)-(+)-1-Phenyl-2,2,2-trifluoroethanol
CAS:	340-06-7
MF:	C8H7F3O
MW:	176.14
EINECS:	206-430-7
Product Categories:	Alcohols, Hydroxy Esters and Derivatives;Chiral Compounds
Mol File:	340-06-7.mol

(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Chemical Properties

Boiling point	73-76 °C9 mm Hg(lit.)
density	1.3 g/mL at 25 °C(lit.)
refractive index	n20/D 1.462(lit.)
Fp	184 °F
storage temp.	Inert atmosphere,Room Temperature
pka	11.91±0.10(Predicted)
form	Liquid
color	Clear colorless to pale yellow
optical activity	[α]20/D +31.3±0.5°, neat
BRN	2327547

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Usage And Synthesis

Uses	(S)?-?(+)?-?α-?(Trifluoromethyl)?benzyl Alcohol is used in the synthesis of metal-organic framework compounds which may have mesoporous properties.
Purification Methods	Purify the chiral alcohols by fractional distillation preferably in a vacuum. [Morrison & Ridgeway Tetrahedron Lett 573 1969, NMR: Pirkle & Beare J Am Chem Soc 90 6250 1968.] The racemate [340-05-6] has b 52-54o/2mm,57-59o/2mm, 64-65o/5mm, d 4 20 1.293, n D 20 1.457, and the 2-carbobenzoyl derivative has m 137-138o [Mosher et al. J Am Chem Soc 78 4374 1956]. [Beilstein 6 IV 3043.]

(S)-(+)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Preparation Products And Raw materials

Raw materials	Trifluoroacetophenone
Preparation Products	(R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL-->(R)-(+)-1-PHENYL-1-PROPANOL-->Ethyl L(-)-lactate

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