4-Methylbenzophenone

4-Methylbenzophenone Basic information
Product Name:4-Methylbenzophenone
Synonyms:P-TOLYL PHENYL KETONE;P-METHYLBENZOPHENONE;PHENYL P-TOLYL KETONE;PHENYL 4-TOLYL KETONE;P-BENZOYL TOLUENE;(4-methylphenyl)phenyl-methanon;4-METHYLBENZOPHENONE;(4-METHYLPHENYL)PHENYLMETHANONE
CAS:134-84-9
MF:C14H12O
MW:196.24
EINECS:205-159-1
Product Categories:Aromatics;Mutagenesis Research Chemicals;Aromatic Benzophenones & Derivatives (substituted);Benzophenone;Organic Photoinitiators;Polymerization Initiators;134-84-9
Mol File:134-84-9.mol
4-Methylbenzophenone Structure
4-Methylbenzophenone Chemical Properties
Melting point 56.5-57 °C (lit.)
Boiling point 326 °C (lit.)
density 0.9926
vapor pressure 0.059Pa at 25℃
refractive index 1.5920 (estimate)
Fp 143 °C
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline Powder or Crystals
color White to beige
Odorfaint odor
Water Solubility Insoluble in water.
Merck 14,7317
BRN 1909310
InChIKeyWXPWZZHELZEVPO-UHFFFAOYSA-N
LogP3.69 at 25℃
CAS DataBase Reference134-84-9(CAS DataBase Reference)
NIST Chemistry ReferenceMethanone, (4-methylphenyl)phenyl-(134-84-9)
EPA Substance Registry System4-Methylbenzophenone (134-84-9)
Safety Information
Hazard Codes Xi
Risk Statements 22-36/38-36/37/38
Safety Statements 24/25-36-26
WGK Germany 3
RTECS DJ1750000
Hazard Note Harmful/Irritant
TSCA Yes
HS Code 29143990
MSDS Information
ProviderLanguage
Phenyl p-tolyl ketone English
ACROS English
SigmaAldrich English
ALFA English
4-Methylbenzophenone Usage And Synthesis
Chemical Propertieswhite to beige crystalline powder or crystals
UsesBenzophenone estrogenicity toxicity structure activity.
Uses4-Methylbenzophenone is used as clear coatings for wood, plastic and metal, overprint varnish.
Uses4-Methylbenzophenone may be used as a reference standard for the determination of the analyte in breakfast cereals, paperboard food packaging and packed milk by various chromatography techniques.
Synthesis Reference(s)Journal of the American Chemical Society, 82, p. 1223, 1960 DOI: 10.1021/ja01490a047
Tetrahedron Letters, 40, p. 3109, 1999 DOI: 10.1016/S0040-4039(99)00476-1
Synthesis, p. 776, 1977 DOI: 10.1055/s-1977-24573
General Description4-Methylbenzophenone is a photo-initiator for printing inks, mainly applied to the cardboard boxes used for packing. It is reported to be a non-genotoxic carcinogen. However, it can contaminate foodstuffs when it comes in contact with the package contents.
Flammability and ExplosibilityNotclassified
Safety ProfilePoison by intraperitoneal route. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification MethodsCrystallise the ketone from MeOH, Et2O (m 58-59o) or pet ether. The cis-oxime has m 154o(153-156o) (from EtOH), and the trans-oxime has m 114-116o (from pet ether). [Beilstein 7 H 440, 7 III 2127, 7 IV 1403.]
4-Methylbenzophenone Preparation Products And Raw materials
Raw materials4-Methylbenzhydrol-->p-Tolualdehyde-->Bromobenzene
Preparation Products4-methylbenzhydrylamine
4-Benzoylbiphenyl TOLUALDEHYDES N,N-Dimethylformamide Methylbenzophenone PHENYL RESIN 4-Methylbenzophenone (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Diphenyl ether Benzophenone 2,2',4,4'-Tetrahydroxybenzophenone PHENYL VALERATE 2-METHYLBENZOPHENONE 3-Methylbenzophenone 4,4'-Dimethylbenzophenone 4-Methoxybenzophenone Phenyl salicylate Phenylacetic acid Benzophenone imine

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