ChemicalBook Product Catalog API Antiparasitic drugs Anthelmintic ansamitocin P-3

ansamitocin P-3

ansamitocin P-3 Basic information
Product Name:ansamitocin P-3
Synonyms:2'-De(acetylmethylamino)-2'-methylmaytansine;2'-De[acetyl(methyl)amino]-2'-methylmaytansine;Anasamitocin P-3;Nsc292222;Tam 330;Tam-330;Ansamitosin P 3;ANSAMITOCIN P-3
CAS:66584-72-3
MF:C32H43ClN2O9
MW:635.14
EINECS:
Product Categories:Cell Signaling and Neuroscience;Cytoskeleton and Extracellular Matrix;Microtobule Inhibitors
Mol File:66584-72-3.mol
ansamitocin P-3 Structure
ansamitocin P-3 Chemical Properties
Melting point 190-192℃
Boiling point 833.1±65.0 °C(Predicted)
density 1.29
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO: 100 mg/mL (157.45 mM);Ethanol: 55 mg/mL (86.60 mM)
pka9.82±0.70(Predicted)
form Solid
color White to Off-White
Water Solubility Water: Insoluble
Safety Information
Hazard Codes Xn
Risk Statements 20/22-36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS OQ2293000
HS Code 2941900000
MSDS Information
ansamitocin P-3 Usage And Synthesis
DescriptionAnsamitocin P 3 is a macrocyclic antitumor antibiotic that works by depolymerizing microtubules in both interphase and mitosis, and perturbs chromosome segregation.
UsesAnsamitocin P-3 is an antitumor agent that binds to cell division protein FtsZ in Actinosynnema pretiosum.
DefinitionChEBI: A polyketide antibiotic that is isolated from Actinosynnema pretiosum and also exhibits antitumour activity.
ansamitocin P-3 Preparation Products And Raw materials
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Hydroxyecdysone Maytansinol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether beta-Sitosterol hydroxygenkwanin ANSAMITOCIN P-3 alpha-Terpineol beta-Eudesmol MOSLOFLAVONE alpha-Cyperone
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