| Chemical Properties | 3-Aminoacetophenone is yellow to light brown crystalline powder
|
| Uses | 3'-Aminoacetophenone has potential anti-bacterial properties in addition to being used in the synthesis of selective antagonists at human A2B adenosine receptors. As well, it is used in the synthesis
of HIV-1 Integrase Inhibitors. |
| Uses | 3′-Aminoacetophenone (3-Acetylaniline) was used as reagent during the asymmetric total synthesis of pactamycin. It was used as starting reagent during the synthesis of curcumin mimics with substituted sulfonyl group. |
| Definition | ChEBI: 3'-Aminoacetophenone is an aromatic ketone. |
| Synthesis Reference(s) | Synthetic Communications, 26, p. 973, 1996 DOI: 10.1080/00397919608003701 |
| General Description | 3′-Aminoacetophenone acts as bifunctional coupling reagent during the synthesis of pyrimidines. |
| Safety Profile | Moderately toxic by ingestion. Mddly toxic by skin contact. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NO,. See also AROMATIC AMINES. |
| Purification Methods | Recrystallise it from EtOH or aqueous EtOH (m 99.5o). The thiosemicarbazone has m 202-204o (from EtOH). [Beilstein 14 H 45, 14 IV 96.] |
