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| | Dihydrochelerythrine Basic information |
| Product Name: | Dihydrochelerythrine | | Synonyms: | Dihydrochelerythrine (12,13-Dihydrochelerythrine);Dihydrochelerythrine;12,13-Dihydro-1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridine;12,13-Dihydro-1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridine;12,13-Dihydrochelerythrine;[1,3]Benzodioxolo[5,6-c]phenanthridine, 12,13-dihydro-1,2-dimethoxy-12-methyl-;1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine;1,2-dimethoxy-12-methyl-12,13-dihydro[1,3]benzodioxolo[5,6-c]phenanthridine | | CAS: | 6880-91-7 | | MF: | C21H19NO4 | | MW: | 349.38 | | EINECS: | 200-258-5 | | Product Categories: | | | Mol File: | 6880-91-7.mol |  |
| | Dihydrochelerythrine Chemical Properties |
| Melting point | 164-165 °C | | Boiling point | 565.9±50.0 °C(Predicted) | | density | 1.291±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO : 50 mg/mL (143.11 mM; Need ultrasonic and warming) | | form | Powder | | pka | 2.36±0.20(Predicted) |
| | Dihydrochelerythrine Usage And Synthesis |
| Description | Dihydrochelerythrine is a benzophenanthridine alkaloid that has been found in Bocconia arborea and has diverse biological activities. It is active against S. aureus, S. faecalis, and C. albicans (MIC = 1.87 μg/ml for all). Dihydrochelerythrine inhibits secretion of the hepatitis B virus (HBV) antigens HBsAg and HBeAg from HepG2 2.2.15 cells (IC50s = <0.05 μM for both). It is cytotoxic to HCT8, BGC-823, and A2780 cancer cells (IC50s = 1.4, 0.4, and 3.5 μM, respectively). | | Uses | Dihydrochelerythrine is synthesized as a potential G-quadrulpex DNA stabilizing agent. It is used in phamacokinetic study of chelerythrine metabolites in agro-products. | | Definition | ChEBI: Dihydrochelerythrine is a benzophenanthridine alkaloid. |
| | Dihydrochelerythrine Preparation Products And Raw materials |
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