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| | (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Basic information |
| Product Name: | (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid | | Synonyms: | (2R,4R)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID;BOC-(2R,4R)-(+)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID;BOC-CIS-4-HYDROXY-D-PROLINE;BOC-D-CISHYP-OH;N-T-BOC-CIS-4-HYDROXY-D-PROLINE;N-BOC-CIS-4-HYDROXY-D-PROLINE;N-ALPHA-BUTOXYCARBONYL-CIS-4-HYDROXY-D-PROLINE;N-BOC-CIS-6-HYDROXY-D-PROLINE | | CAS: | 135042-12-5 | | MF: | C10H17NO5 | | MW: | 231.25 | | EINECS: | 621-971-2 | | Product Categories: | | | Mol File: | 135042-12-5.mol |  |
| | (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Chemical Properties |
| Melting point | 146-151 °C | | alpha | +48～+52°(c=0.67,MeOH,24℃) | | Boiling point | 390.9±42.0 °C(Predicted) | | density | 1.312 | | storage temp. | 2-8°C | | pka | 3.80±0.40(Predicted) | | form | powder to crystal | | color | White to Light yellow | | optical activity | [α]22/D +50.0°, c = 1 in methanol | | InChIKey | BENKAPCDIOILGV-RNFRBKRXSA-N |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29339900 |
| | (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Usage And Synthesis |
| Chemical Properties | White solid | | Uses | N-Boc-cis-4-hydroxy-D-proline can be used:
- As a starting material in the synthesis of DNA mimicking pyrrolidine peptide nucleic acid (PNA) analog.
- In the synthesis of biologically important macrocyclic dilactones.
- As an intermediate in the synthesis of histamine H3?receptor antagonists.
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| | (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Preparation Products And Raw materials |
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