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| | CAFTARIC ACID Basic information |
| Product Name: | CAFTARIC ACID | | Synonyms: | MONO-(3,4-DIHYDROXYCINNAMOYL)-TARTARIC ACID;(2R,3R)-(-)-CAFTARIC ACID);(2E,3R)-2-[[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL)OXY]-3-HYDROXYBUTANEDIOIC ACID;CAFTARIC ACID;2-Caffeoyl-L-tartaric acid;(2R,3R)-2-[(3,4-Dihydroxy-trans-cinnamoyl)oxy]-3-hydroxybutanedioic acid;(2R,3R)-2-[[(E)-1-Oxo-3-(3,4-dihydroxyphenyl)-2-propenyl]oxy]-3-hydroxybutanedioic acid;(2R,3R)-2-[[(E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3-hydroxybutanedioic acid | | CAS: | 67879-58-7 | | MF: | C13H12O9 | | MW: | 312.23 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Miscellaneous Natural Products | | Mol File: | 67879-58-7.mol |  |
| | CAFTARIC ACID Chemical Properties |
| Melting point | 124～125℃ | | Boiling point | 618.2±55.0 °C(Predicted) | | density | 1.694±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Methanol (Slightly), Water (Slightly, Heated, Sonicated) | | pka | 2.18±0.25(Predicted) | | form | neat | | color | White to Pale Beige | | Odor | at 100.00?%. odorless | | Stability: | Hygroscopic | | LogP | 1.147 (est) |
| WGK Germany | 3 | | HS Code | 2918290000 |
| | CAFTARIC ACID Usage And Synthesis |
| Description | Caftaric acid is a phenolic acid and a tartaric acid ester form of caffeic acid . It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) free radicals in a cell-free assay (EC50 = 20.4 μM) and inhibits oxidation of LDL isolated from human plasma by 97.6% compared to vehicle control in vitro when used at a concentration of 5 μM. Caftaric acid is the main phenolic compound in V. vinifera white, pink, and black table grapes as well as various wines. In vivo, caftaric acid content in dietary-administered red wine positively correlates with inhibition of protein carbonylation and decreased superoxide dismutase (SOD), glutathione peroxidase (Gpx), and catalase activities in mice. | | Uses | Caftaric Acid is used in cancer therapy as an anticancer drug. Affecting the up regulation or down regulation of drug transporters or cytochrome p450 enzymes. Also provides antioxidant effects, found in wines. | | Definition | ChEBI: Caftaric acid is a hydroxycinnamic acid. | | target | LDL | NO |
| | CAFTARIC ACID Preparation Products And Raw materials |
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