Mepacrine hydrochloride

Mepacrine hydrochloride Basic information
Product Name:Mepacrine hydrochloride
Synonyms:QUINACRINE DIHYDROCHLORIDE DIHYDRATE;QUINACRINE HYDROCHLORIDE, DIHYDRATE;6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxy-acridindihydr;6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridinedihydroc;atabrinehydrochloridedihydrate;hloride2h2-o;mepacrinehcl;mepacrinehydrochloridedihydrate
CAS:6151-30-0
MF:C23H36Cl3N3O3
MW:508.91
EINECS:
Product Categories:
Mol File:6151-30-0.mol
Mepacrine hydrochloride Structure
Mepacrine hydrochloride Chemical Properties
Melting point 247 °C
storage temp. Store at -20°C
solubility DMSO: 10 mg/mL (19.65 mM);;
Water Solubility 2.8 g/100 mL
CAS DataBase Reference6151-30-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-37/39
MSDS Information
ProviderLanguage
ACROS English
Mepacrine hydrochloride Usage And Synthesis
Chemical Propertiesbright yellow powder
UsesQuinacrine Dihydrochloride Dihydrate is a phophoslipase A2 inhibitor.
General DescriptionQunacrine is no longer available in theUnited States. It can be considered one of the most toxic ofthe antimalarial drugs even though, at one time, it was commonlyused. It acts at many sites within the cell includingintercalation of DNA strands, succinic dehydrogenase andmitochondrial electron transport, and cholinesterase. It maybe tumorgenic and mutagenic and has been used as a sclerosingagent. Because it is an acridine dye, quinacrine cancause yellow discoloration of the skin and urine.
Mepacrine hydrochloride Preparation Products And Raw materials
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