Diphenyl sulfone

Diphenyl sulfone Basic information
Product Name:Diphenyl sulfone
Synonyms:Benzene, 1,1'-sulfonylbis-;Difenylsulfon;dlphenylsulfone;phenylsulphone;s-127;s-97;Sulfone, diphenyl;Diphenylsulfone,99%
CAS:127-63-9
MF:C12H10O2S
MW:218.27
EINECS:204-853-1
Product Categories:Flexibilizer,acaricide and organic synthesis;Biochemistry;Color Former & Related Compounds;Diphenyl Sulfones (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Reagents for Oligosaccharide Synthesis;Sensitizer;127-63-9
Mol File:127-63-9.mol
Diphenyl sulfone Structure
Diphenyl sulfone Chemical Properties
Melting point 123-129 °C (lit.)
Boiling point 379 °C (lit.)
density 1.36
vapor pressure 0.001Pa at 50℃
refractive index 1.5200 (estimate)
Fp 184°C
storage temp. Sealed in dry,Room Temperature
solubility >14mg/l
form Crystalline Powder
color White
Water Solubility insoluble
Merck 14,3332
BRN 1910573
InChIKeyKZTYYGOKRVBIMI-UHFFFAOYSA-N
LogP2.61
CAS DataBase Reference127-63-9(CAS DataBase Reference)
NIST Chemistry ReferenceDiphenyl sulfone(127-63-9)
EPA Substance Registry SystemDiphenylsulfone (127-63-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS SX2400000
TSCA Yes
HS Code 29309070
ToxicityLD50 orally in rats: >2 g/kg, Residue Rev. 36, 240 (1971)
MSDS Information
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Diphenyl sulfone English
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Diphenyl sulfone Usage And Synthesis
Chemical PropertiesDiphenyl sulfone is a sulfone compound having two S-phenyl substituents. It is a crystalline powder that is soluble in organic solvents. It has been found in plants like Gnidia glauca and Dioscorea bulbifera. It has a role as a plant metabolite.
Diphenyl sulfone
Diphenyl sulfone is formed under certain conditions by the action of aqueous sulfuric acid on benzene. It is used as a high temperature solvent. Such high temperature solvents are useful for processing highly rigid polymers, e.g., PEEK, which only dissolve in very hot solvents.

UsesPhenyl Sulphone undergoes deoxygenation with Mg-MeOH at room temperature.
UsesOvicide; acaricide.
UsesDiphenyl sulfone was identified as the preferred solvent. Diphenyl sulfone is chemically and thermally stable as compared to dimethyl sulfoxide.
DefinitionChEBI: A sulfone compound having two S-phenyl substituents. It has been found in plants like Gnidia glauca and Dioscorea bulbifera.
Synthesis Reference(s)The Journal of Organic Chemistry, 50, p. 1784, 1985 DOI: 10.1021/jo00210a053
Synthesis, p. 342, 1974
Tetrahedron Letters, 21, p. 689, 1980 DOI: 10.1016/S0040-4039(00)71446-8
Flammability and ExplosibilityNotclassified
Purification MethodsCrystallise the sulfone from diethyl ether. It has been purified by zone melting. [Beilstein 6 H 300, 6 IV 1490.]
DIMETHYL DIPHENYL SULFONE 4,4'-DICARBOXYLATE 3,3',4,4'-TETRACHLORODIPHENYL SULFONE 4,4'-DIAMINO-15N2-DIPHENYL SULFONE Tetradifon 4-NITRO-4'-AMINODIPHENYL SULFONE PHENYL RESIN 4,4'-Bis(p-hydroxyphenyl)diphenyl sulfone 4,4'-Di(Glycidylather)-Diphenyl Sulfone 4,4'-Di(2-Hydroxyethoxy) Diphenyl Sulfone VITAS-BB TBB000179 POTASSIUM DIPHENYL SULFONE-3-SULFONATE) 2-(Phenylsulfonyl)aniline N-[4-(4-CHLORO-BENZENESULFONYL)-PHENYL]-ACETAMIDE PHENYL VALERATE N,N'-4,4'-Diphenyl sulfone bismaleimide O-NITRO DIPHENYL SULFONE DIBENZOTHIOPHENE SULFONE 4,4'-Dichlorodiphenyl sulfone

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