2,4-Lutidine

2,4-Lutidine Basic information
Product Name:2,4-Lutidine
Synonyms:2,4-LUTIDINE 98+%;2,4-DIMETHYLPYRIDINE(2,4-LUTIDINE);Dimethylpyridine, 2,4-: (2,4-Lutidine);2,4-Lutidine, 98+% 500ML;2,4-DIMETHYLPYRIDINE FOR SYNTHESIS;2,4-Lutidine 99%;alpha,gamma-Dimethylpyridine;Pyridine,2,4-dimethyl-
CAS:108-47-4
MF:C7H9N
MW:107.15
EINECS:203-586-8
Product Categories:Building Blocks;C7;Biochemistry;Chemical Synthesis;Heterocyclic Building Blocks;Pyridines;Organics;Heterocyclic Compounds;Reagents for Oligosaccharide Synthesis
Mol File:108-47-4.mol
2,4-Lutidine Structure
2,4-Lutidine Chemical Properties
Melting point -60 °C (lit.)
Boiling point 159 °C (lit.)
density 0.927 g/mL at 25 °C (lit.)
vapor pressure 3.28hPa at 25℃
refractive index n20/D 1.499(lit.)
FEMA 4389 | 2,4-DIMETHYLPYRIDINE
Fp 99 °F
storage temp. Flammables area
solubility 350g/l
form Liquid
pka6.99(at 25℃)
color Colorless to Light yellow to Light orange
Odorat 0.01 % in dipropylene glycol. smoky phenolic
Odor Typesmoky
Water Solubility 15 g/100 mL (20 ºC)
Sensitive Hygroscopic
JECFA Number2151
BRN 1506
InChIKeyJYYNAJVZFGKDEQ-UHFFFAOYSA-N
LogP1.9
CAS DataBase Reference108-47-4(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 2,4-dimethyl-(108-47-4)
EPA Substance Registry System2,4-Dimethylpyridine (108-47-4)
Safety Information
Hazard Codes T,F,Xi
Risk Statements 10-23/24/25-36/37/38-25-20/21-20/21/22
Safety Statements 16-26-36/37/39-45
RIDADR UN 1992 3/PG 3
WGK Germany 3
RTECS OK9400000
8
TSCA Yes
HazardClass 3
PackingGroup III
HS Code 29333999
MSDS Information
ProviderLanguage
2,4-Lutidine English
SigmaAldrich English
ACROS English
ALFA English
2,4-Lutidine Usage And Synthesis
Chemical PropertiesClear pale yellow liquid, discoloring over time
Chemical PropertiesColorless to pale-yellow clear liquid.
Uses2,4-Lutidine, can be used as a building block in the synthesis of various chemical compounds. It is also used tobacco and aroma component.
DefinitionChEBI: 2,4-Dimethylpyridine is a member of methylpyridines.
Aroma threshold valuesHigh strength odor, recommend smelling in a 0.01% solution or less.
Purification MethodsDry it with Linde type 5A molecular sieves, BaO or sodium, and fractionally distil it. The distillate (200g) is heated with *benzene (500mL) and conc HCl (150mL) in a Dean and Stark apparatus on a water bath until water no longer separates, and the temperature just below the liquid reaches 80o. When cold, the supernatant *benzene is decanted, and the 2,4-lutidine hydrochloride, after washing with a little *benzene, is dissolved in water (350mL). After removing any *benzene by steam distillation, an aqueous solution of NaOH (80g) is added, and the free lutidine is steam distilled. It is isolated by saturating the distillate with solid NaOH and distilling it through a short column. The precipitation cycle is repeated, then the final distillate is partly frozen in an apparatus at -67.8-68.5o (cooled by acetone/CO2). The crystals are collected, then melted and distilled. [Kyte et al. J Chem Soc 4454 1960.] Alternative purifications are via the picrate m 183-184o (from H2O). [Clarke & Rothwell J Chem Soc 1885 1960], or the hydrobromide [Warnhoff J Org Chem 27 4587 1962]. The latter is precipitated from a solution of lutidine in *benzene by passing dry HBr gas: the salt is recrystallised from CHCl3/methyl ethyl ketone, then decomposed with NaOH, and the free base is extracted into Et2O, dried, evaporated and the residue is distilled. [Beilstein 20 H 244, 20 II 180, 20 III/IV 2718, 20/6 V 19.]
Dimethyl sulfone Bathocuproine 2-Chloro-3-cyanopyridine N,N-Dimethylformamide Poly(dimethylsiloxane) QUINOXALIN-5-AMINE 2,4-Lutidine 3,5-Lutidine,99%,Lutidine,98%,3,5-LUTIDINE, 98+%,3,5-LUTIDINE 3,5-DIMETHYLPYRIDINE,3 5-LUTIDINE STANDARD FOR GC 5,7-DIMETHYL[1,8]NAPHTHYRIDIN-2-AMINE 4-Pyridoxic acid 2,6-Lutidine 2,4,6-Collidine Dimethyl sulfoxide 2,5-LUTIDINE 98+% Pyridoxine 2,3-LUTIDINE,2,3-DIMETHYLPYRIDINE(2,3-LUTIDINE),2,3-LUTIDINE 98+%,2,3-Lutidine,99%,2,3-LUTIDINE/2,3-DIMETHYL PYRIDINE N,N-Dimethylacetamide 3,4-Lutidine98%,3,4-LUTIDINE 98%,3,4-LUTIDINE 3,4-DIMETHYLPYRIDINE

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.