2-Amino-4,6-dimethylpyridine

2-Amino-4,6-dimethylpyridine Basic information

Product Name:	2-Amino-4,6-dimethylpyridine
Synonyms:	Pyridine, 2-amino-4,6-dimethyl-;2-amino-4,6-dimethylpyridine (6-amino-2,4,-lutidine);2,4-Dimethyl-6-aminopyridine;6-Amino-2,4dimethylpyridine;4,6-dimethyl-2-pyridylamine;6-AMINO-2,4-LUTIDINE 98+%;6-Amino-2,4-lutidine, 4,6-Dimethylpyridin-2-amine;2-AMino-4,6-diMehtylpyridine
CAS:	5407-87-4
MF:	C7H10N2
MW:	122.17
EINECS:	226-470-9
Product Categories:	Heterocycle-Pyridine series;Amines;Pyridine series;Pyridines;Pyridine
Mol File:	5407-87-4.mol

2-Amino-4,6-dimethylpyridine Chemical Properties

Melting point	63-64 °C (lit.)
Boiling point	235 °C (lit.)
density	1.0959 (rough estimate)
refractive index	1.6100 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	7.62±0.35(Predicted)
form	Crystalline Powder
color	White to light brown
InChIKey	BRBUBVKGJRPRRD-UHFFFAOYSA-N
CAS DataBase Reference	5407-87-4(CAS DataBase Reference)
NIST Chemistry Reference	2-Pyridinamine, 4,6-dimethyl-(5407-87-4)
EPA Substance Registry System	2-Pyridinamine, 4,6-dimethyl- (5407-87-4)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-22
Safety Statements	26-37/39
WGK Germany	3
RTECS	US1818000
Hazard Note	Irritant
HS Code	2933399990

MSDS Information

Provider	Language
SigmaAldrich	English

2-Amino-4,6-dimethylpyridine Usage And Synthesis

Chemical Properties	White to off-white crystalline
Uses	Organic intermediate.
Uses	2-Amino-4,6-dimethylpyridine, can be used in the synthesis of various chemical compounds having therapeutic activity, such as in preparation of quinoline and quinoxaline compounds having anticancer activity.
Purification Methods	Recrystallise this base from hexane, ether/pet ether or benzene. Residual benzene is removed over paraffin-wax chips in an evacuated desiccator. The dipicrate crystallises from EtOH and has m 205-207o(dec). [Beilstein 22 III/IV 4210.]

2-Amino-4,6-dimethylpyridine Preparation Products And Raw materials

Raw materials	Hydrochloric acid-->Xylene-->Sodium amide-->2,4-Lutidine
Preparation Products	2-BROMO-4,6-DIMETHYLPYRIDINE-->CARBAMIC ACID, N-(4,6-DIMETHYL-2-PYRIDINYL)-,1,1-DIMETHYLETHYL ESTER-->Ethyl N-(4,6-dimethylpyridin-2-yl)carbamate-->JM 42-->Propanamide, N-(4,6-dimethyl-2-pyridinyl)-

2-Amino-4,6-dimethylpyridine 2,4-Lutidine 2-Amino-6-methylpyridine 6-METHYL-4-(TRIFLUOROMETHYL)PYRID-2-YL HYDRAZINE 2-Amino-3-picoline 3-Aminopyridine 6-Aminocaproic acid Glycine 2-(DIMETHYLAMINO)-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)NICOTINONITRILE 5,7-DIMETHYLPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE 2,6-Lutidine 4,6-DIMETHYL-2-PIPERIDINONICOTINONITRILE Tris(hydroxymethyl)aminomethane AMINO ACIDS 3-Aminophenol N,N-Dimethyl-1,4-phenylenediamine 4-Dimethylaminopyridine 4-Methylpyridin-2-amine

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