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| | 6-PHENYL-3(2H)-PYRIDAZINONE Basic information |
| Product Name: | 6-PHENYL-3(2H)-PYRIDAZINONE | | Synonyms: | 6-Phenyl-2,3-dihydropyridazine-3-one;3-phenyl-1H-pyridazin-6-one;3-Phenyl-6-pyridazinone;2,3-Dihydro-3-oxo-6-phenylpyridazine, (6-Oxo-1,6-dihydropyridazin-3-yl)benzene;6-Phenyl-3(2H)-pyridazinone;6-PHENYL-3(2H)-PYRIDAZINONE;8-(2-hydroxypropan-2-yl)-2-furo[2,3-h][1]benzopyranone;JR-8471, 6-Phenyl-3-(2H)-pyridazinone, 97% | | CAS: | 2166-31-6 | | MF: | C10H8N2O | | MW: | 172.18 | | EINECS: | 218-505-1 | | Product Categories: | Building Blocks;Heterocyclic Building Blocks;Pyridazines | | Mol File: | 2166-31-6.mol |  |
| | 6-PHENYL-3(2H)-PYRIDAZINONE Chemical Properties |
| Melting point | 201-204 °C(lit.) | | density | 1.20±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 11.05±0.40(Predicted) | | color | White to Light yellow | | λmax | 249nm(HCl aq.)(lit.) | | InChIKey | IJUIPRDMWWBTTQ-UHFFFAOYSA-N |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 2933998090 |
| | 6-PHENYL-3(2H)-PYRIDAZINONE Usage And Synthesis |
| Uses | 6-Phenylpyridazin-3(2H)-one is a reagent in the preparation of cyclase activator Runcaciguat, a compound used in the treatment of kidney disease and non-proliferative diabetic retinopathy. | | General Description | 6-Phenyl-3(2H)-pyridazinone is a pyridazinone derivative that can be prepared from 4,5- dihydro-6-phenyl-3(2H)-pyridazinone. It is reported to be a weak positive inotropic agent. 6-Phenyl-3(2H)-pyridazinone forms the core of compounds that show a potential antiplatelet activity. |
| | 6-PHENYL-3(2H)-PYRIDAZINONE Preparation Products And Raw materials |
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