ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Fluoropyridine 3-FLUORO-2-FORMYLPYRIDINE

3-FLUORO-2-FORMYLPYRIDINE

3-FLUORO-2-FORMYLPYRIDINE Basic information
Product Name:3-FLUORO-2-FORMYLPYRIDINE
Synonyms:3-FLUOROPYRIDINE-2-CARBALDEHYDE;3-FLUOROPYRIDINE-2-CARBOXALDEHYDE;3-FLUORO-2-FORMYLPYRIDINE;3-Fluoropyridine-2-carboxaldehyde 97%;3-Fluoropyridine-2-carboxaldehyde97%;2-Pyridinecarboxaldehyde,3-fluoro-(9CI);3-FLURO-2-FORMYLPYRIDINE;3-FLUOROPYRIDINE-2-CARBOXALDEHYDE/3-FLUORO-2-FORMYLPYRIDINE
CAS:31224-43-8
MF:C6H4FNO
MW:125.1
EINECS:690-026-4
Product Categories:Fluorine series;PYRIDINE;pharmacetical;Pyridine series;Aldehyde;Building Blocks
Mol File:31224-43-8.mol
3-FLUORO-2-FORMYLPYRIDINE Structure
3-FLUORO-2-FORMYLPYRIDINE Chemical Properties
Melting point 49 °C
Boiling point 112°C/50mmHg(lit.)
density 1.269±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility soluble in Methanol
pka1.25±0.10(Predicted)
form Solid
color White to Green to Brown
Water Solubility Slightly soluble in water.
CAS DataBase Reference31224-43-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
Hazard Note Harmful
HS Code 2933399990
MSDS Information
3-FLUORO-2-FORMYLPYRIDINE Usage And Synthesis
Uses3-Fluoropyridine-2-carboxaldehyde is used to prepare taxoids derived from 9β-dihydrobaccatin-9,10-acetals with anti-tumor activities. It is also an intermediate used to synthesize S-3578 derivatives with potent activities against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa.
Synthesis Reference(s)Tetrahedron, 39, p. 2009, 1983 DOI: 10.1016/S0040-4020(01)91919-2
3-FLUORO-2-FORMYLPYRIDINE Preparation Products And Raw materials
Preparation ProductsN-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine-->3-FLUORO-N-METHYLPYRID-2-YLMETHYLAMINE
6-AMINO-5-BROMO-3-FLUOROPYRIDINE-2-CARBOXAMIDE 6-AMINO-3-FLUOROPYRIDINE-2-CARBOXAMIDE 2-Acetyl-3-fluoropyridine 6-ACETYL-5-FLUOROPYRIDINE-2-CARBONITRILE 3-FLUOROPYRIDINE-2-CARBOXYLIC ACID 6-Chloro-3-fluoro-pyridine-2-carboxylic acid 3,5-DIFLUOROPYRIDINE-2-CARBOXAMIDE 6-ETHYNYL-3-FLUOROPYRIDINE-2-CARBOXAMIDE 6-(ACETYLAMINO)-3-FLUORO-4-METHYLPYRIDINE-2-CARBOXAMIDE 3-FLUORO-2-FORMYLPYRIDINE LITHIUM 3-FLUOROPYRIDINE-2-CARBOXYLATE 5-BROMO-3-FLUOROPICOLINIC ACID 2-CHLORO-5-FLUORO-6-FORMYLPYRIDINE 3-FLUORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 6-ACETYL-5-FLUOROPYRIDINE-2-CARBOXAMIDE 3,5-Difluoropicolinic acid 6-(ACETYLAMINO)-3-FLUOROPYRIDINE-2-CARBOXAMIDE 6-AMINO-3-FLUORO-4-METHYLPYRIDINE-2-CARBOXAMIDE
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