4-Methylsalicylic acid

4-Methylsalicylic acid Basic information
Product Name:4-Methylsalicylic acid
Synonyms:2,4-cresoticacid;2-hydroxy-4-methyl-benzoicaci;4-Methyl-2-hydroxybenzoic acid;Benzoic acid, 2-hydroxy-4-methyl-;gamma-Cresotic acid;gamma-cresoticacid;m-Homosalicylic acid;m-homosalicylicacid
CAS:50-85-1
MF:C8H8O3
MW:152.15
EINECS:200-068-3
Product Categories:Aromatics;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;bc0001
Mol File:50-85-1.mol
4-Methylsalicylic acid Structure
4-Methylsalicylic acid Chemical Properties
Melting point 173-177 °C (lit.)
Boiling point 234.6°C (rough estimate)
density 1.2143 (rough estimate)
refractive index 1.4945 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
form Powder
pkapK1:3.17 (25°C)
color White to grayish-beige
Water Solubility Soluble in water 10 g/L @ 20℃.
Merck 14,2580
BRN 2208140
InChIKeyNJESAXZANHETJV-UHFFFAOYSA-N
CAS DataBase Reference50-85-1(CAS DataBase Reference)
NIST Chemistry Reference2-Hydroxy-4-methylbenzoic acid(50-85-1)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-37/39
WGK Germany 3
RTECS GP3920100
HS Code 29182900
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
4-Methylsalicylic acid Usage And Synthesis
Chemical Properties4-Methylsalicylic acid is white to greyish-beige powder
Uses4-Methylsalicylic acid is similar to salicylic acid. Used in manufacturing of dyes.
UsesIn manufacture of dyes.
Uses4-Methylsalicylic acid was used to inhibit the medium chain acyl- CoA synthetase.
Definition4-Methylsalicylic acid is a monohydroxybenzoic acid consisting of salicylic acid having a methyl group at the 4-position.
General DescriptionThe heteroleptic tris-cyclometalated iridium(III) complex with 4-methylsalicylic acid (Msal) was synthesized and characterized.
Purification MethodsCrystallise the acid from water. It sublimes at 130o/11mm. [Beilstein 10 H 233, 10 II 137, 10 III 521, 10 IV 617.]
4-Methylsalicylic acid Preparation Products And Raw materials
Preparation Products9H-Xanthen-9-one, 3,6-dimethyl--->METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE-->methyl 4-(bromomethyl)-2-methoxybenzoate-->METHYL 2-METHOXY-4-METHYLBENZOATE-->2-HYDROXY-5-IODO-4-METHYLBENZOIC ACID-->Methyl 2-Methoxy-4-Methyl-5-nitrobenzoate-->2-Hydroxy-4-Methyl-5-nitro-benzoic acid Methyl ester-->2-Hydroxy-4-Methyl-5-nitro-benzoic acid
SPECS AQ-776/42801114 ETHYL 2,6-DIHYDROXY-4-METHYLBENZOIC ACID Salicylic acid Ethyl 2-(Chlorosulfonyl)acetate Ascoric Acid 4-Methylsalicylic acid PSOROMIC ACID CARDINAL RED Acetylsalicylic acid 5-Nitrosalicylic acid 2,5-Dihydroxyterephthalic acid 4-Trifluoromethylsalicylic acid Methyl salicylate O-METHYLSALICYLIC ACID,3-Methylsalicylic acid,3-Methylsalicylic acid ,99% CHLOROPHOSPHONAZO III 3-Nitrosalicylic acid 5-methylsalicylic acid(2-hydroxy-5-methylbenzoic acid),5-METHYLSALICYLIC ACID 3,5,6,8-TETRAHYDROXY-1-METHYL-9,10-DIOXO-7-((2S,3S,4S,5R,6S)-3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YL)-9,10-DIHYDRO-ANTHRACENE-2-CARBOXYLIC ACID

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