PYRAZOPHOS

PYRAZOPHOS Basic information
Product Name:PYRAZOPHOS
Synonyms:AFUGAN;Afugan powder;AFUGAN(R);ETHYL-2-DIETHOXYPHOSPHINOTHIOYLOXY-5-METHYLPYRAZOLO[1,5-A]-PYRIMIDINE-6-CARBOXYLATE;PYRAZOPHOS;Pyrazophos emulsion(content>15%);Pyrazophos powder(content>55%);O,O-DIETHYL-O-6-ETHOXYCARBONYL-5-METHYL-PYRAZOLO [1,5-A]PYRIMIDIN-2-YL-PHOSPHOROTHIONATE
CAS:13457-18-6
MF:C14H20N3O5PS
MW:373.36
EINECS:236-656-1
Product Categories:OrganophosphorusAlphabetic;Fungicides;P;Pesticides;PU - PZ;Alpha sort;N-PPesticides;Pesticides&Metabolites
Mol File:13457-18-6.mol
PYRAZOPHOS Structure
PYRAZOPHOS Chemical Properties
Melting point 51℃
density 1.38±0.1 g/cm3(Predicted)
vapor pressure 2.2 x 10-4 Pa (50 °C)
storage temp. APPROX 4°C
pka-1.37±0.40(Predicted)
form neat
Water Solubility 4.2 mg l-1 (25 °C)
Merck 13,8052
BRN 577209
EPA Substance Registry SystemPyrazophos (13457-18-6)
Safety Information
Hazard Codes Xn,N
Risk Statements 20/22-50/53
Safety Statements 36/37-46-60-61
RIDADR 2783
WGK Germany 3
RTECS TF2035000
HazardClass 6.1(b)
PackingGroup III
ToxicityLD50 in rats, marmots, rabbits (mg/kg): 140, 184, 435 orally (Smit)
MSDS Information
PYRAZOPHOS Usage And Synthesis
UsesFungicide.
UsesPyrazophos is a systemic fungicide that provides both protective and curative control of various fungal diseases such as powdery mildew (Podosphaera) on apples, stone fruits, bush fruits and strawberries, Erysiphe in cucurbits and tomatoes, Uncinula on vines and leaf blotch (Rhynchosporium) in cereals.
UsesPyrazophos is an anticholinesterase pesticide used on fruits and vegetables and can be determined by gas chromatography/mass spectrometry and liquid chromatography with fluorescence detection.
DefinitionChEBI: A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A fungicide used to control Erysiphe, Helminthosporium and ital>Rhynchospium in cereals.
Metabolic pathwayLimited information is available to describe the degradation and metabolic fate of pyrazophos. Hydrolytic cleavage of the P-O-pyrazolopyrimidine linkage is the primary metabolic pathway. Oxidative desulfuration of pyrazophos to pyrazophos-oxon is only a minor pathway, observed in the plant metabolism study (Scheme 1).
MetabolismIts mode of action is believed to be the inhibition of melanin biosynthesis and the development of appressoria by fungal conidia. Formulation is available as emulsifiable concentrate (EC: 30%). Application rates on Oidium spp. are in the range of 15–30 g a.i./hl.
DegradationPyrazophos (1) is hydrolysed in acidic or alkaline solution (PM).
PYRAZOPHOS Preparation Products And Raw materials
3-amino-1H-pyrazol-5-ol 6-METHYLPYRAZOLO[1,5-A]PYRIMIDINE PYRAZOPHOS SOLUTION 100UG/ML IN TOLUENE 1ML PYRAZOPHOS PYRAZOLO[1,5-A]PYRIMIDINE 3-Amino-5-hydroxypyrazole PYRAZOPHOS SOLUTION 100UG/ML IN ACETONITRILE 1ML

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