3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE

3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Basic information
Product Name:3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
Synonyms:3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE;3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE, 0.5M SOLUTION IN TETRAHYDROFURAN;3,4-difluorophenylmagnesium bromide solution;3,4-Difluorophenylmagnesium bromide,0.5M solution in THF;3,4-Difluorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal§3;3,4-Difluorophenylmagnesium bromide solution 0.5 in THF;3,4-DifluorophenylMagnesiuM broMide, 0.50 M solution in 2-Methyltetrahydrofuran, SpcSeal;3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE 0.5M Tetrahydrofuran
CAS:90897-92-0
MF:C6H3BrF2Mg
MW:217.29
EINECS:
Product Categories:Aryl;Grignard Reagents;Organometallic Reagents
Mol File:90897-92-0.mol
3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Structure
3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Chemical Properties
Boiling point 65 °C
density 0.965 g/mL at 25 °C
Fp 1 °F
storage temp. 2-8°C
form Solution
color Yellow to dark brown
Water Solubility Reacts with water.
Sensitive Air & Moisture Sensitive
Safety Information
Hazard Codes F,C,Xn
Risk Statements 11-14-19-22-34-40-36/37
Safety Statements 16-26-33-36/37/39-45-36/37
RIDADR UN 2924 3/PG 2
WGK Germany 1
Hazard Note Flammable
HazardClass 3
HS Code 29319090
MSDS Information
ProviderLanguage
SigmaAldrich English
3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Usage And Synthesis
Chemical PropertiesTan liquid
Uses3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Uses3,4-Difluorophenylmagnesium bromide can be used:
  • To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
  • In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
  • In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
  • In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.

3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Preparation Products And Raw materials
Preparation Products1-BOC-4-(3,4-DIFLUOROPHENYL)-4-HYDROXYPIPERIDINE
3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE,3,5-DIFLUOROPHENYLMAGNESIUM BROMIDE, 0.5M SOLUTION IN TETRAHYDROFURAN,3,5-difluorophenylmagnesium bromide solution 3-METHYLBENZYLMAGNESIUM CHLORIDE 3,5-DICHLOROPHENYLMAGNESIUM BROMIDE 3,4-DIMETHOXYPHENYLMAGNESIUM BROMIDE 3,5-DIMETHOXYBENZYL BROMIDE 3 5-DIMETHYOXYPHENYLMAGNESIUM CHLORIDE 3 4 5-TRIFLUOROPHENYLMAGNESIUM BROMIDE 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE 3,4-DICHLOROPHENYLMAGNESIUM BROMIDE 3,5-DIMETHYLPHENYLMAGNESIUM BROMIDE 3,4,5-TRIMETHOXYPHENYLMAGNESIUM BROMIDE SOLUTION 0.5M IN TETRAHYDROFURAN 3,5-dimethyl-4-methoxyphenylmagnesium bromide 3-FLUOROPHENYLMAGNESIUM BROMIDE PHENYLMAGNESIUM BROMIDE 4-FLUOROPHENYLMAGNESIUM BROMIDE 3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE Methylmagnesium Bromide PENTAFLUOROPHENYLMAGNESIUM BROMIDE

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