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| | 8-Bromoquinoline Basic information |
| | 8-Bromoquinoline Chemical Properties |
| Melting point | 58-59 °C | | Boiling point | 112-113 °C/0.5 mmHg (lit.) | | density | 1.594 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.672(lit.) | | Fp | >230 °F | | storage temp. | Inert atmosphere,2-8°C | | form | Liquid After Melting | | pka | 2.33±0.17(Predicted) | | Specific Gravity | 1.594 | | color | Clear yellow to yellow-brown | | Sensitive | Light Sensitive | | InChIKey | PIWNKSHCLTZKSZ-UHFFFAOYSA-N | | CAS DataBase Reference | 16567-18-3(CAS DataBase Reference) | | NIST Chemistry Reference | Quinoline, 8-bromo-(16567-18-3) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29334900 |
| | 8-Bromoquinoline Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 8-Bromoquinoline may be used in the following studies:
- Synthesis of 8-(dimesitylboryl)quinolone (ambiphilic molecule).
- Direct synthesis of 5H-pyrido[3,2,1-ij]quinolin-3-one, via palladium catalyzed coupling reaction with acrolein.
- Preparation of 8-(1-hydroxyethyl)quinolone.
- Preparation of 8-quinolylcyclopentadienyl metal complexes, via reaction with zincated cyclopentadienyl derivatives of Fe, Mn and Re in the presence of bis(triphenylphosphine)palladium(0).
- Synthesis of n,n′-biquinolines by a coupling reaction using tris(triphenylphosphine)nickel(0) and a zerovalent pyridine-nickel complex.
| | General Description | 8-Bromoquinoline is a quinolone derivative. It is widely employed for the synthesis of dyes, food colors, pharmaceutical reagents, pH indicators and in various industrial processes. Its molecule bears a pyridyl group. It undergoes direct heteroarylation reaction with various heteroaromatic compounds in the presence of a palladium catalyst to afford polyheteroaromatic derivatives. |
| | 8-Bromoquinoline Preparation Products And Raw materials |
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