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| | Tropisetron Basic information |
| Product Name: | Tropisetron | | Synonyms: | TROPISETRON;1H-Indole-3-carboxylic acid (1β,5β)-8-methyl-8-azabicyclo[3.2.1]octan-3α-yl ester;1H-Indole-3-carboxylic acid, endo-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester;Tropisetron (ICS 205930);8-methyl-8-azabicyclo(3.2.1)oct-3-ylester,endo-1h-indole-3-carboxylicaci;icf205-930;3-TROPANYL-INDOLE-3-CARBOXYLATE HYDROCHL ORIDE(ICS-205,930, NOVOBAN;3-TROPANYL-INDOLE-3-CARBOXYLATE METHIODI DE ICS-205,930, METHIODI | | CAS: | 89565-68-4 | | MF: | C17H20N2O2 | | MW: | 284.35 | | EINECS: | 1806241-263-5 | | Product Categories: | | | Mol File: | 89565-68-4.mol |  |
| | Tropisetron Chemical Properties |
| Melting point | 201-202 °C | | Boiling point | 448.5±35.0 °C(Predicted) | | density | 1.26 | | storage temp. | Inert atmosphere,2-8°C | | solubility | H2O: soluble | | form | solid | | pka | 15.38±0.30(Predicted) | | color | white | | CAS DataBase Reference | 89565-68-4(CAS DataBase Reference) |
| | Tropisetron Usage And Synthesis |
| Description | Tropisetron is the third selective 5HT3-antagonist, after ondansetron and granisetron, to
be introduced for the management of nausea and vomiting induced by cancer
chemotherapy. Similar to the other two 5HT3-antagonists, vopisetron is superior to
metoclopramide. The compound has also been reported to have antiarrhythmic
activity. | | Originator | Sandoz (Switzerland) | | Uses | A substance that is used to prevent nausea and
vomiting caused by chemotherapy. | | Definition | ChEBI: An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine. | | Brand name | Novaban | | Hazard | Human systemic effects. |
| | Tropisetron Preparation Products And Raw materials |
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