(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Basic information

Product Name:	(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
Synonyms:	H-DL-SER(3,4-DIHYDROXYPHENYL)-OH;H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE;H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SER-OH;DL-DOPS;DL-THREO-BETA-(3,4-DIHYDROXYPHENYL)SERINE;DL-THREO-DOPS;D,L-(3,4-DIHYDROXYPHENYL)-SERINE;BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE
CAS:	3916-18-5
MF:	C9H11NO5
MW:	213.19
EINECS:	223-480-5
Product Categories:	Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	3916-18-5.mol

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Chemical Properties

Melting point	202-205°C (dec.)
Boiling point	549.8±50.0 °C(Predicted)
density	1.608±0.06 g/cm3(Predicted)
storage temp.	-15°C
solubility	ethanol: 50 mg/mL Solutions should be freshly prepared.
pka	2.09±0.24(Predicted)
form	powder
color	off-white to yellow-tan

Safety Information

WGK Germany	2
RTECS	VT9626000

MSDS Information

Provider	Language
SigmaAldrich	English

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Usage And Synthesis

Chemical Properties	White Solid
Uses	A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian.
Definition	ChEBI: Droxidopa is a serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension It has a role as a prodrug, a vasoconstrictor agent and an antihypertensive agent. It is a L-tyrosine derivative and a member of catechols.

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Preparation Products And Raw materials

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