Olivetol

Olivetol Basic information
Product Name:Olivetol
Synonyms:5-PENTYL 1,3-BENZENEDIOL;5-N-PENTYLRESORCINOL;5-AMYL RESORCINOL;AURORA KA-7378;OLIVETOL;5-n-amylresorcinol;5-pentyl-3-benzenediol;5-pentyl-resorcino
CAS:500-66-3
MF:C11H16O2
MW:180.24
EINECS:207-908-8
Product Categories:API intermediates;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;500-66-3
Mol File:500-66-3.mol
Olivetol Structure
Olivetol Chemical Properties
Melting point 46-48 °C(lit.)
Boiling point 164 °C
density 1.068±0.06 g/cm3(Predicted)
Fp >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka9.59±0.10(Predicted)
color Colourless to Beige
Stability:Light Sensitive
InChIInChI=1S/C11H16O2/c1-2-3-4-5-9-6-10(12)8-11(13)7-9/h6-8,12-13H,2-5H2,1H3
InChIKeyIRMPFYJSHJGOPE-UHFFFAOYSA-N
SMILESC1(O)=CC(CCCCC)=CC(O)=C1
CAS DataBase Reference500-66-3(CAS DataBase Reference)
NIST Chemistry Reference1,3-Benzenediol, 5-pentyl-(500-66-3)
EPA Substance Registry SystemOlivetol (500-66-3)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/39
WGK Germany 3
RTECS VH2880000
HS Code 2907290090
MSDS Information
ProviderLanguage
Olivetol English
SigmaAldrich English
Olivetol Usage And Synthesis
Chemical PropertiesOlivetol is an off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.
Physical propertieslight purple to brown crystalline mass.
ApplicationOlivetol is a precursor in various syntheses of tetrahydrocannabinol.
UsesOlivetol was used as a template molecule in the synthesis of molecularly imprinted polymer (MIP). It was also used as an inhibitor of (S)-mephenytoin 4'-hydroxylase activity of recombinant CYP2C19.
DefinitionChEBI: Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.
Preparationolivetol can also be formed through hydrolysis of intermediate polyketide CoAs or spontaneous cyclization.
synthesis of Olivetol
Synthesis Reference(s)The Journal of Organic Chemistry, 42, p. 3456, 1977 DOI: 10.1021/jo00441a036
General DescriptionOlivetol appears as off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). (NTP, 1992)
Air & Water ReactionsSensitive to air. Insoluble in water.
Reactivity ProfileOlivetol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.
Fire HazardOlivetol is probably combustible.
Biological ActivityOlivetol (5-Pentylresorcinol, 5-n-Amylresorcinol) is a naturally occurring organic compound being a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.
SafetyOlivetol is still a very new product. It has not been researched nearly enough to prove it's safe to use. So far, no one has reported any adverse side effects as far as we know. Until more information is available, carefully control your THC intake instead of relying on an untested gelcap.
Mode of actionWhen you look at olivetol's molecular structure, it'll look very familiar. It's as if someone took a THC molecule and sliced it in two. Olivetol, like THC, works by binding with the CB1 receptors that exist all over your body and brain. But, olivetol is thought to be smaller and stickier than THC, so that helps it reduce a raging high in two ways. First, it slips into any open receptors before THC can get there to block them—so you won't get any higher. Second, it bumps into THC molecules that are already lodged in a CB1 receptor to knock them loose and take their place. That's how it brings you down.
According to numerous personal accounts, olivetol works, but we don't know exactly how it does so. More research and investigation is needed, but in theory it's very similar to how Narcan acts to reverse opiate overdoses.
ETHYLENE Glycerol Acetic acid Methylparaben Lead styphnate 4-Hydroxybenzoic acid Olivetol 2-Nitroresorcinol 2-Hydroxyphenylacetic acid DIHYDROXY BENZALDEHYDE 2-Methylresorcinol Resorcinol 4-Hydroxybenzaldehyde Triclosan 4-Methoxyphenol 4-Chlororesorcinol Phenylpentane 4-METHYLRESORCINOL

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.