2-Oxobutyric acid

2-Oxobutyric acid Basic information

Product Name:	2-Oxobutyric acid
Synonyms:	PROPIONYLFORMIC ACID;2-Ketobutanoic acid;2-oxo-butanoicaci;alpha-Ketobutric acid;alpha-Oxobutyrate;alpha-Oxo-n-butyric acid;Butanoicacid,2-oxo-;Butyric acid, 2-oxo-
CAS:	600-18-0
MF:	C4H6O3
MW:	102.09
EINECS:	209-986-9
Product Categories:	Pharmaceutical Raw Materials;Aliphatics;Enzyme substrates
Mol File:	600-18-0.mol

2-Oxobutyric acid Chemical Properties

Melting point	30-34 °C(lit.)
Boiling point	84 °C20 mm Hg(lit.)
density	1.2000
FEMA	3723 \| 2-OXOBUTYRIC ACID
refractive index	1.3972 (estimate)
Fp	179 °F
storage temp.	Store at +2°C to +8°C.
solubility	H2O: soluble0.1g/mL, clear
pka	2.5(at 25℃)
form	liquid
color	White to Almost white
Specific Gravity	1.3972 (20/4℃)
PH	3.11(1 mM solution);2.38(10 mM solution);1.79(100 mM solution);
Odor	at 1.00 % in propylene glycol. sweet brown caramel creamy lactonic
Odor Type	caramellic
JECFA Number	589
BRN	1700514
InChIKey	TYEYBOSBBBHJIV-UHFFFAOYSA-N
LogP	-0.75
CAS DataBase Reference	600-18-0(CAS DataBase Reference)
NIST Chemistry Reference	Butanoic acid, 2-oxo-(600-18-0)
EPA Substance Registry System	2-Oxobutyric acid (600-18-0)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

2-Oxobutyric acid Usage And Synthesis

Chemical Properties	COLOURLESS TO ALMOST COLOURLESS CRYSTALS
Chemical Properties	2-Oxobutyric acid has a sweet, brown, caramel, creamy odor.
Occurrence	Reported found in beer and black tea.
Uses	A substrate for the determination of lactate dehydrogenase isoenzymes.This compound is suitable for lactate dehydrogenase (LDH) related research.
Uses	2-Oxobutyric acid (α-ketobutyric acid) may be used as an analytical reference standard for the determination of the analyte in K562 cells by high-performance liquid chromatography with fluorescence detection and in drinking water at low microgram per liter concentrations by ion chromatography technique.
Definition	ChEBI: A 2-oxo monocarboxylic acid that is the 2-oxo derivative of butanoic acid.
Taste threshold values	Taste characteristics at 25 ppm: sweet, brown, creamy, caramellic with a fatty nuance.
General Description	2-Oxobutyric acid is mainly found in the hydrolysates of proteins, reportedly being formed by the degradation of threonine.

2-Oxobutyric acid Preparation Products And Raw materials

Raw materials	D-2-Aminobutyric acid
Preparation Products	ALPHA-KETOBUTYRIC ACID SODIUM SALT-->5-BROMO-3-METHYLINDOLE-->bucloxic acid-->ETHYL3-METHYL-2-INDOLECARBOXYLATE-->Ethyl 3-bromo-2-oxobutyrate-->Ethyl 3-oxobutanoate sodium salt-->Butanoic acid, 2-oxo-, 1,1-dimethylethyl ester-->3-Methyl-4-phenylquinoline-2-carboxylic acid-->1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-Methyl--->(2S,3R)-2-Amino-3-(4-hydroxy-phenyl)-butyric acid

Login