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| | N-(2-Acetamido)iminodiacetic acid Basic information |
| | N-(2-Acetamido)iminodiacetic acid Chemical Properties |
| Melting point | 219 °C (dec.)(lit.) | | Boiling point | 325.64°C (rough estimate) | | density | 1.4957 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.5010 (estimate) | | storage temp. | room temp | | solubility | 1 M NaOH: 0.05 M at 20 °C, clear, colorless | | form | Powder | | color | White to almost white | | PH | 1.5-3.0 (25℃, 0.01M in H2O) | | PH Range | 6.0 - 7.2 | | pka | 6.6(at 25℃) | | Water Solubility | soluble | | λmax | λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.05 | | Merck | 14,147 | | BRN | 1787181 | | InChIKey | QZTKDVCDBIDYMD-UHFFFAOYSA-N | | LogP | -3.12 at 20℃ | | CAS DataBase Reference | 26239-55-4(CAS DataBase Reference) | | EPA Substance Registry System | Glycine, N-(2-amino-2-oxoethyl)-N-(carboxymethyl)- (26239-55-4) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | TSCA | Yes | | HazardClass | IRRITANT | | HS Code | 29241900 |
| | N-(2-Acetamido)iminodiacetic acid Usage And Synthesis |
| Description | ADA is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2. | | Chemical Properties | N-(2-Acetamido)iminodiacetic acid is white to almost white powder
| | Uses | Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4).Used to prepare immobilized pH gradients. | | Uses | N-(2-Acetamido)iminodiacetic acid is buffer for biological systems and chelator for metals.
| | Uses | ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column. | | Application | ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column.
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4). Used to prepare immobilized pH gradients. | | Definition | ChEBI: 2,2'-[(2-amino-2-oxoethyl)imino]diacetic acid is a tricarboxylic acid amide that is a Good's buffer substance, pKa = 6.6 at 20 ℃. It is a dicarboxylic acid, a tricarboxylic acid amide and an ADA. It is functionally related to a nitrilotriacetic acid. It is a conjugate acid of a 2,2'-[(2-amino-2-oxoethyl)imino]diacetate(1-). | | Flammability and Explosibility | Notclassified | | Purification Methods | Dissolve ADA in water, add one equivalent of NaOH solution (to final pH of 8-9), then acidify with HCl to precipitate the free acid. This is filtered off, washed with water and dried in vacuo. [Beilstein 4 IV 2441.] |
| | N-(2-Acetamido)iminodiacetic acid Preparation Products And Raw materials |
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