| Uses | Propantheline is used for treating stomach ulcers. |
| Uses | Anticholinergic. |
| Definition | ChEBI: Propantheline is a member of xanthenes. |
| Brand name | Pro-Banthine (Searle). |
| Pharmacology | The pharmacological action of propantheline is qualitatively similar to atropine. It has a
weaker effect on the CNS than atropine. Unlike atropine, it exhibits greater ganglioblocking action than antimuscarinic action. Moreover, upon overdose it causes neuromuscular
curare-like blockage. |
| Synthesis | Propanetheline, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-
ylcarbonyl) oxy]ethyl]-2-propanaminium bromide (14.1.11), is synthesized by reacting xanthen-9-carboxylic acid chloride with 2-di-iso-propylaminoethanol, giving the ester (14.1.10),
which upon reaction with methylbromide turns into the quaternary salt, propantheline
(14.1.11) [12,13]. 
|
| Veterinary Drugs and Treatments | Proparacaine is a rapid acting topical anesthetic useful for a variety
of ophthalmic procedures including tonometry (intraocular pressure
measurement), relief of corneal pain to facilitate examination,
biopsy/sample collection, and to distinguish between corneal and
uveal pain. Proparacaine primarily anesthetizes the cornea; with
limited penetration into conjunctiva. Anesthesia is of short duration
(5 – 10 minutes). |
