ChemicalBook Product Catalog Chemical Reagents Organic reagents Hydrazine SALICYLIDENE SALICYLHYDRAZIDE

SALICYLIDENE SALICYLHYDRAZIDE

SALICYLIDENE SALICYLHYDRAZIDE Basic information
Product Name:SALICYLIDENE SALICYLHYDRAZIDE
Synonyms:2-HYDROXYBENZYLIDENE SALICYLHYDRAZIDE;2-HYDROXYBENZYLIDENE 2-HYDROXYBENZHYDRAZIDE;2-hydroxy-benzoicaci[(2-hydroxyphenyl)methylene]hydrazide;(2-hydroxybenzylidene)salicylohydrazide;Salicylidenesalicylhydrazide,97%;2-Hydroxybenzylidene 2-hydroxybenzhydrazide, NSC 87864, SCS;SALICYLIDENE SALICYLHYDRAZIDE;SALICYLIDENE SALICYLHYDRAZONE
CAS:3232-36-8
MF:C14H12N2O3
MW:256.26
EINECS:221-773-2
Product Categories:GABA/Glycine receptor;Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
Mol File:3232-36-8.mol
SALICYLIDENE SALICYLHYDRAZIDE Structure
SALICYLIDENE SALICYLHYDRAZIDE Chemical Properties
Melting point 280-284°C
storage temp. Store at RT
solubility DMSO: ~20 mg/mL
form solid
color off-white
BRN 2944701
CAS DataBase Reference3232-36-8(CAS DataBase Reference)
EPA Substance Registry SystemBenzoic acid, 2-hydroxy-, [(2-hydroxyphenyl)methylene]hydrazide (3232-36-8)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36-37
WGK Germany 3
TSCA Yes
HS Code 29280000
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
SALICYLIDENE SALICYLHYDRAZIDE Usage And Synthesis
UsesSCS is a selective inhibitor of β1-containing GABAA receptors.
DefinitionChEBI: 2-hydroxy-N'-[(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]benzohydrazide is a member of salicylamides.
Biological ActivityPotent and selective partial inhibitor of β 1-containing GABA A receptors (IC 50 values are 4.5, 5.3 and 7.9 nM at α 2 β 1 γ 1 θ , α 2 β 1 γ 1 and α 2 β 1 γ 2s GABA A receptors respectively). May bind allosterically to a novel site on GABA A receptor.
SALICYLIDENE SALICYLHYDRAZIDE Preparation Products And Raw materials
Raw materialsSALICYLIC (ALPHA-METHYLBENZYLIDENE)HYDRAZIDE-->Salicylhydrazide-->Ethyl 2-hydroxybenzoate-->Methyl salicylate-->Salicylaldehyde-->Salicylic acid
SALOR-INT L458163-1EA SALOR-INT L451347-1EA SALOR-INT L105902-1EA SALOR-INT L400270-1EA SALOR-INT L269360-1EA SALICYLIDENE SALICYLHYDRAZIDE 3-HYDROXY-N'-[(1E)-(2-HYDROXY-1-NAPHTHYL)METHYLENE]-2-NAPHTHOHYDRAZIDE N'-[(1E)-(5-BROMO-2-HYDROXYPHENYL)METHYLENE]-3-HYDROXY-2-NAPHTHOHYDRAZIDE SALOR-INT L483648-1EA SALOR-INT L105120-1EA 3-HYDROXY-N'-[(1E)-(2-HYDROXYPHENYL)METHYLENE]-2-NAPHTHOHYDRAZIDE SALOR-INT L104809-1EA SALOR-INT L400610-1EA SALOR-INT L105899-1EA SALOR-INT L463396-1EA SALOR-INT L106313-1EA N'-[(E)-(5-BROMO-2-ETHOXYPHENYL)METHYLIDENE]-2-HYDROXYBENZENECARBOHYDRAZIDE SALOR-INT L106062-1EA
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